32865-79-5Relevant academic research and scientific papers
6-Methylpurine derived sugar modified nucleosides: Synthesis and in vivo antitumor activity in D54 tumor expressing M64V-Escherichia coli purine nucleoside phosphorylase
Hassan, Abdalla E.A.,Abou-Elkhair, Reham A.I.,Parker, William B.,Allan, Paula W.,Secrist, John A.
, p. 616 - 622 (2016)
Impressive antitumor activity has been observed with fludarabine phosphate against tumors that express Escherichia coli purine nucleoside phosphorylase (PNP) due to the liberation of 2-fluoroadenine in the tumor tissue. 6-Methylpurine (MeP) is another cyt
