3289-00-7 Usage
Uses
Used in Pharmaceutical Research:
2-(p-tert-Butylphenyl)acetohydroxamic acid is used as a chelating agent for metal ions, which is crucial in various chemical and biological processes. Its ability to bind metal ions can be utilized in the development of drugs targeting metal-dependent enzymes or in the treatment of metal toxicity.
Used in Cancer Treatment:
In the field of oncology, 2-(p-tert-Butylphenyl)acetohydroxamic acid is used as a potential therapeutic agent for cancer treatment. It functions by inhibiting histone deacetylases, enzymes that play a significant role in gene regulation and are often dysregulated in cancer cells. This inhibition can lead to the reactivation of tumor suppressor genes and the suppression of oncogenes, thereby exhibiting anti-cancer properties.
Used in Anti-Inflammatory Applications:
2-(p-tert-Butylphenyl)acetohydroxamic acid has shown potential as an anti-inflammatory agent in experimental studies. Its use in this application is based on its ability to modulate inflammatory pathways and reduce the production of inflammatory mediators, which can be beneficial in treating conditions characterized by chronic inflammation.
Used in Antifungal Applications:
In the field of antifungal research, 2-(p-tert-Butylphenyl)acetohydroxamic acid is used as a potential antifungal agent. Its antifungal properties have been demonstrated in various experimental studies, suggesting that it could be a candidate for the development of new antifungal drugs to combat fungal infections.
Used in Drug Development:
2-(p-tert-Butylphenyl)acetohydroxamic acid is also used in the development of new drugs, leveraging its chemical properties and potential therapeutic effects. Its multifaceted applications in different areas of medicine highlight its importance in the discovery and design of novel pharmaceutical agents.
Check Digit Verification of cas no
The CAS Registry Mumber 3289-00-7 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 3,2,8 and 9 respectively; the second part has 2 digits, 0 and 0 respectively.
Calculate Digit Verification of CAS Registry Number 3289-00:
(6*3)+(5*2)+(4*8)+(3*9)+(2*0)+(1*0)=87
87 % 10 = 7
So 3289-00-7 is a valid CAS Registry Number.
InChI:InChI=1/C12H17NO2/c1-12(2,3)10-6-4-9(5-7-10)8-11(14)13-15/h4-7,15H,8H2,1-3H3,(H,13,14)
3289-00-7Relevant academic research and scientific papers
P(III)-Assisted Electrochemical Access to Ureas via in situ Generation of Isocyanates from Hydroxamic Acids
Meng, Haiwen,Sun, Kunhui,Xu, Zhimin,Tian, Lifang,Wang, Yahui
supporting information, p. 1768 - 1772 (2021/03/26)
An external oxidant-free protocol for the generation of isocyanates from hydroxamic acids assisted by trivalent phosphine under mild electrochemical conditions was reported. The process started with the anodic oxidation of hydroxamic acids, followed by reacting with phosphine to form corresponding alkoxyphosphoniums and subsequent rearrangement with the release of tri-substituted phosphine oxide as the driving force to give isocyanates, which were trapped by N-based nucleophiles to produce various ureas. This method provides a broadly applicable procedure to access isocyanate intermediates under mild electrochemical conditions.
