328974-80-7

Basic information

• Product Name: 5-ETHENYL-L-PROLINE METHYL ESTER HYDROCHLORIDE
• Synonyms: H-L-PRO(5S-VINYL)-OME HCL;5-ETHENYL-L-PROLINE METHYL ESTER HYDROCHLORIDE;L-Proline, 5-ethenyl-, methyl ester, (5S)- (9CI);Methyl (2S,5S)-5-vinyl-2-pyrrolidinecarboxylate hydrochloride;5-Ethenyl-L-Pro methyl ester
• CAS NO: 328974-80-7
• Molecular Formula: C8H14ClNO2
• Molecular Weight: 191.66
• Product Categories: GLYCINESCAFFOLD;PYRROLE;CARBOXYLICESTER
• Mol File: 328974-80-7.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 5-ETHENYL-L-PROLINE METHYL ESTER HYDROCHLORIDE(CAS DataBase Reference)
• NIST Chemistry Reference: 5-ETHENYL-L-PROLINE METHYL ESTER HYDROCHLORIDE(328974-80-7)
• EPA Substance Registry System: 5-ETHENYL-L-PROLINE METHYL ESTER HYDROCHLORIDE(328974-80-7)

Safety Data

• Hazardous Substances Data: 328974-80-7(Hazardous Substances Data)

Upstream product

• 210345-05-4 (S)-5-(2-Hydroxy-ethyl)-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 195964-65-9 (2S)-5-allyl-pyrrolidine-1,2-dicarboxylic acid 1-tert-butyl ester 2-methyl ester 
• 328974-72-7 (2S,5S)-N-tert-butoxycarbonyl-5-vinylpyrrolidine-2-carboxylic acid methyl ester 

Relevant articles and documents

A sequential electrochemical oxidation - Olefin metathesis strategy for the construction of bicyclic lactam based peptidomimetics

A sequential electrochemical amide oxidation - ring closing olefin metathesis sequence has been used to overcome problems associated with the synthesis of seven-membered ring lactam containing bicyclic peptidomimetics. The synthesis of several previously unavailable bicyelic lactam building blocks for constructing constrained thyroliberin analogs is described.