Tetrahedron Letters p. 4639 - 4642 (1998)
Update date:2022-09-26
Topics:
Beal, Laura M.
Moeller, Kevin D.
A sequential electrochemical amide oxidation - ring closing olefin metathesis sequence has been used to overcome problems associated with the synthesis of seven-membered ring lactam containing bicyclic peptidomimetics. The synthesis of several previously unavailable bicyelic lactam building blocks for constructing constrained thyroliberin analogs is described.
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