329003-81-8

Upstream product

• 72141-41-4 (4-nitro-phenyl)-piperazin-1-yl-methanone 
• 122-04-3 4-nitro-benzoyl chloride 
• 329040-80-4 (4-nitro-phenyl)-{4-[2-(4-nitro-phenyl)-ethyl]-piperazin-1-yl}-methanone 

Relevant academic research and scientific papers

Synthesis and class III type antiarrhythmic activity of 4-Aroyl (and Aryl)-1-aralkylpiperazines

The synthesis and in vitro Class III antiarrhythmic activity of several 4-aroyl (and aryl)-1-aralkylpiperazine and piperidine derivatives are described. Among several potent compounds identified in the series, RWJ-28810 (3), with its EC20 of 3 nM, ranks as one of the most potent (in vitro) compounds reported. (C) 2000 Elsevier Science Ltd.