329013-06-1 Usage
Description
(S)-3-AMINO-3-(1H-INDOL-3-YL)-PROPIONIC ACID, also known as indole-3-propionic acid (IPA), is a chemical compound derived from the amino acid tryptophan. It features an amino group and an indole ring, and is naturally present in the human body as a metabolite of gut bacteria. IPA has garnered interest for its potential neuroprotective, anti-inflammatory, and antioxidant properties, making it a promising candidate for the treatment of various neurological disorders, inflammatory conditions, and in reducing oxidative stress.
Uses
Used in Pharmaceutical Industry:
(S)-3-AMINO-3-(1H-INDOL-3-YL)-PROPIONIC ACID is used as a therapeutic agent for its potential neuroprotective and anti-inflammatory effects, targeting a range of neurological disorders and inflammatory conditions. Its antioxidant properties also contribute to its potential use in reducing oxidative stress in the body.
Used in Research and Development:
IPA serves as a subject of ongoing research, further exploring its potential applications in medicine and pharmacology. This includes investigating its mechanisms of action, optimizing its delivery methods, and assessing its efficacy and safety in clinical settings.
Used in Dietary Supplements:
Given its natural occurrence in the human body and potential health benefits, (S)-3-AMINO-3-(1H-INDOL-3-YL)-PROPIONIC ACID may be utilized as an ingredient in dietary supplements aimed at supporting cognitive health, reducing inflammation, and promoting overall well-being.
Check Digit Verification of cas no
The CAS Registry Mumber 329013-06-1 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 3,2,9,0,1 and 3 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 329013-06:
(8*3)+(7*2)+(6*9)+(5*0)+(4*1)+(3*3)+(2*0)+(1*6)=111
111 % 10 = 1
So 329013-06-1 is a valid CAS Registry Number.
329013-06-1Relevant articles and documents
Synthesis and binding activity of endomorphin-1 analogues β-amino acids
Cardillo, Giuliana,Gentilucci, Luca,Melchiorre, Paolo,Spampinato, Santi
, p. 2755 - 2758 (2000)
Endomorphin-1 (Tyr-Pro-Trp-PheNH2) has been proposed as the most potent endogenous ligand of the μ-opioid receptors. In this paper, we describe the synthesis of some endomorphin-1 based tetrapeptides in which a residue of the sequence Tyr-Pro-Trp-PheNH2 is replaced by the corresponding β-isomer. These novel peptides showed different affinities for the opioid receptors labeled with [3H]-DAMGO in rat brain membranes, depending on the β-amino acid. In particular, the tetrapeptide containing β-Pro (Tyr-β-(R)-Pro-Trp-PheNH2) displayed a higher affinity than endogenous endomorphin-1, as revealed by their K(i) values (0.33 and 11.1 nM, respectively). (C) 2000 Elsevier Science Ltd.
