5814-94-8 Usage
Uses
Used in Pharmaceutical Industry:
3-AMINO-3-(1H-INDOL-3-YL)-PROPIONIC ACID is used as a potential therapeutic agent for various conditions due to its anti-inflammatory and antioxidant properties. It is being investigated for its efficacy in treating inflammatory bowel disease, diabetes, and neurodegenerative disorders, where its ability to modulate immune responses and protect against oxidative stress could be beneficial.
Used in Nutritional Supplements:
In the nutritional supplement industry, 3-AMINO-3-(1H-INDOL-3-YL)-PROPIONIC ACID is used as an additive to promote health and well-being. Its presence in certain vegetables and its natural occurrence in the human gut microbiota suggest that it may contribute to a balanced diet and support overall health.
Used in Research Applications:
3-AMINO-3-(1H-INDOL-3-YL)-PROPIONIC ACID is utilized as a research compound in scientific studies aimed at understanding its role in human health and disease. It serves as a valuable tool for investigating the mechanisms of inflammation, oxidative stress, and metabolic regulation, potentially leading to the development of new therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 5814-94-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 5,8,1 and 4 respectively; the second part has 2 digits, 9 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 5814-94:
(6*5)+(5*8)+(4*1)+(3*4)+(2*9)+(1*4)=108
108 % 10 = 8
So 5814-94-8 is a valid CAS Registry Number.
5814-94-8Relevant academic research and scientific papers
Synthesis and binding activity of endomorphin-1 analogues β-amino acids
Cardillo, Giuliana,Gentilucci, Luca,Melchiorre, Paolo,Spampinato, Santi
, p. 2755 - 2758 (2007/10/03)
Endomorphin-1 (Tyr-Pro-Trp-PheNH2) has been proposed as the most potent endogenous ligand of the μ-opioid receptors. In this paper, we describe the synthesis of some endomorphin-1 based tetrapeptides in which a residue of the sequence Tyr-Pro-Trp-PheNH2 is replaced by the corresponding β-isomer. These novel peptides showed different affinities for the opioid receptors labeled with [3H]-DAMGO in rat brain membranes, depending on the β-amino acid. In particular, the tetrapeptide containing β-Pro (Tyr-β-(R)-Pro-Trp-PheNH2) displayed a higher affinity than endogenous endomorphin-1, as revealed by their K(i) values (0.33 and 11.1 nM, respectively). (C) 2000 Elsevier Science Ltd.
