329218-12-4

Usage

Uses

Used in Pharmaceutical Industry:
(3-BROMO-4-CHLORO-PHENYL)-METHANOL is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure allows it to be a key component in the development of new drugs, contributing to the advancement of medicinal chemistry.
Used in Agrochemical Industry:
In the agrochemical sector, (3-BROMO-4-CHLORO-PHENYL)-METHANOL is employed as an intermediate in the production of agrochemicals. Its role in this industry is vital for the creation of effective and safe products for agricultural use.
Used in Organic Compound Development:
(3-BROMO-4-CHLORO-PHENYL)-METHANOL is utilized as a building block in the development of organic compounds. Its distinctive structure makes it a valuable asset in the synthesis of complex organic molecules for various applications, including but not limited to, research and commercial production.

Upstream product

• 76008-75-8 3-bromo-4-chlorobenzoic acid ethyl ester 
• 42860-10-6 3-bromo-4-chlorobenzoic acid 
• 107947-17-1 methyl 3-bromo-4-chlorobenzoate 
• 1126-46-1 Methyl 4-chlorobenzoate 

Downstream Products

• 1297551-29-1 (+/-)-tert-butyl 2-(3-bromo-4-chlorobenzyl)-2-methylbutanoate 
• 1297551-48-4 (+/-)-tert-butyl 3-(3-bromo-4-chlorophenyl)-2-cyclobutylpropanoate 
• 1297552-67-0 tert-butyl 3-(3-bromo-4-chlorophenyl)-2,2-dimethylpropanoate 
• 1297552-69-2 tert-butyl 3-[3-(benzylamino)-4-chlorophenyl]-2,2-dimethylpropanoate 
• 1297552-70-5 tert-butyl 3-(3-amino-4-chlorophenyl)-2,2-dimethylpropanoate 
• 1297553-13-9 tert-Butyl 3-(4-chloro-3-{[(2S,3R)-2-(4-chlorophenyl)-4,4,4-trifluoro-3-methylbutanoyl]amino}-phenyl)-2,2-dimethylpropanoate 
• 880348-24-3 2-bromo-4-(bromomethyl)-1-chlorobenzene 
• 1297551-31-5 (+/-)-tert-butyl 2-[3-(benzylamino)-4-chlorobenzyl]-2-methylbutanoate 
• 1297551-32-6 (+/-)-tert-butyl 2-(3-amino-4-chlorobenzyl)-2-methylbutanoate 
• 1622068-77-2 3-[3-(2-chloro-5-hydroxymethyl-phenyl)-6-oxo-6H-pyridazin-1-ylmethyl]-benzoic acid methyl ester 
• 1079402-22-4 2-(2-chloro-5-methoxymethylphenyl)-4,4,5,5-tetramethyl-[1,3,2]dioxaborolane 

Relevant academic research and scientific papers

N-[3-(2-CARBOXYETHYL)PHENYL]PIPERIDIN-1-YLACETAMIDE DERIVATIVES AND USE THEREOF AS ACTIVATORS OF SOLUBLE GUANYLATE CYCLASE

The present application relates to novel substituted 2-(piperidin-1-yl)acetamide derivatives, to processes for preparation thereof, to the use thereof for treatment and/or prevention of diseases, and to the use thereof for production of medicaments for treatment and/or prevention of diseases, especially for treatment and/or prevention of cardiovascular diseases.

Synthesis of benzyl alcohol building blocks bearing an aldehyde, pinacol borane or carboxylic acid motif via lithium-bromide exchange

A range of useful disubstituted benzyl alcohol building blocks have been synthesised in multigram quantities in a lithium-bromide exchange to give aldehyde, carboxylic acid and pinacol -boranes in high yields. Georg Thieme Verlag Stuttgart · New York.

N3-SUBSTITUTED IMINOPYRIMIDINONES AS RENIN INHIBITORS, COMPOSITIONS, AND THEIR USE

In its many embodiments, the present invention provides provides certain N3-substituted iminopyrimidinones of Formula (I): and tautomers and stereoisomers thereof, and pharmaceutically acceptable salts of said compounds, said tautomeros and said stereoiso

Substituted 1-benzylcycloalkylcarboxylic acids and the use thereof

The present application relates to novel substituted 1-benzylcycloalkylcarboxylic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases, and to their use for producing medicaments for the treatment and/or prevention of diseases, especially for the treatment and/or prevention of cardiovascular disorders.

INDOLYL-PIPERIDINYL BENZYLAMINES AS BETA-TRYPTASE INHIBITORS

The present invention discloses and claims a series of substituted indolyl-piperidinyl benzylamines of formula (I), wherein R1, R2 and R3 are as described herein. More specifically, the compounds of this invention are inhibitors of β-tryptase and are, therefore, useful as pharmaceutical agents. Additionally, this invention also discloses methods of preparation of substituted indolyl-piperidinyl benzylamines. In one of the embodiments, there is provided the compounds of formula (I) wherein R3 is (II).

SUBSTITUTED 3-PHENYLPROPIONIC ACIDS AND THE USE THEREOF

The present application relates to novel 3-phenylpropionic acid derivatives, to processes for their preparation, to their use for the treatment and/or prevention of diseases and to their use for preparing medicaments for the treatment and/or prevention of diseases, in particular for the treatment and/or prevention of cardiovascular disorders.

Substituted biaryl compounds as factor XIa inhibitors

The present invention provides compounds of Formula (I): or a stereoisomer, tautomer, pharmaceutically acceptable salt or solvate form thereof, wherein the variables A, L, Z, R3, and ring B are as defined herein. The compounds of Formula (I) ar

CALCIUM RECEPTOR MODULATING ARYLALKYLAMINES

The compounds of the invention are represented by the following general structure (I) or a pharmaceutically acceptable salt thereof, and compositions containing them, wherein the variables are defined herein, and their use to reduce or inhibit PTH secretion, including methods for reducing or inhibiting PTH secretion and methods for treatment or prophylaxis of diseases associated with bone disorders, such as osteoporosis, or associated with excessive secretion of PTH, such as hyperparathyroidism. The subject invention also relates to processes for making such compounds as well as to intermediates useful in such processes.

Oxime derivatives for the treatment of dyslipidemia and hypercholesteremia

The present invention relates to compounds of Formula (I) which may be useful in the treatment of diseases, such as, metabolic disorders, dyslipidemia and/or hyperchloesterolemia: 1

Heterocyclic derivatives for the treatment of diabetes and other diseases

The present invention relates to certain substituted heterocycles of Formula (I) which are useful in the treatment of diseases related to lipid and carbohydrate metabolism, such as type 2 diabetes, adipocyte differentiation, uncontrolled proliferation, such as lymphoma, Hodgkin's Disease, leukemia, breast cancer, prostate cancer or cancers in general; and inflammation, such as osteoarthritis, rheumatoid arthritis, Crohn's Disease or Inflammatory Bowel Disease.