329235-34-9Relevant academic research and scientific papers
Concise approach to mono- And disubstituted luotonin A analogs and their cytotoxicity test
Kagawa, Natsuko,Nishimura, Kimiko,Abe, Shinya,Masuko, Takashi,Toyota, Masahiro
, p. 514 - 522 (2019/07/31)
A concise approach for the preparation of luotonin A analogs has been developed. The new synthetic route contains an anion-assisted intramolecular double hetero Diels Alder reaction and a direct oxidative cross coupling reaction. Some synthetic luotonin A analogs show cytotoxic activities against Daudi and Jurkat human cancer cells as potent as camptothecin.
Access to phthalazinones via palladium-catalyzed three-component cycloamino-carbonylation of 2-formylaryl tosylates, hydrazines and CO
Liu, Bin,Zhang, Chunlei,Zhou, Xigeng
supporting information, p. 8282 - 8286 (2016/12/02)
The palladium-catalyzed three-component cycloaminocarbonylation of 2-formylaryl tosylates with hydrazines and carbon monoxide has been established, which provides an efficient method for synthesis of substituted phthalazinones. In addition, by applying this protocol as the key step, Hydralazine can easily be synthesized in 65% yield.
A concise approach to the preparation of 2-hydroxydiarylketones by an intramolecular acyl radical ipso substitution
Motherwell,Vazquez
, p. 9667 - 9671 (2007/10/03)
Substituted 2-hydroxydiarylketones have been simply prepared using an intramolecular acyl radical [1,6] ipso substitution reaction. (C) 2000 Elsevier Science Ltd.
