4998-50-9

Usage

Uses

Used in Pharmaceutical Synthesis:
(2-hydroxy-5-methoxyphenyl)(4-methylphenyl)methanone is utilized as an intermediate in the synthesis of pharmaceuticals, leveraging its unique chemical structure to contribute to the development of new medications.
Used in Organic Compounds Synthesis:
(2-hydroxy-5-methoxyphenyl)(4-methylphenyl)methanone serves as a key component in the synthesis of various organic compounds, where its specific functional groups can be manipulated to create a range of different products.
Used in Antioxidant Applications:
Due to its antioxidant properties, (2-hydroxy-5-methoxyphenyl)(4-methylphenyl)methanone can be employed in applications requiring the neutralization of free radicals, potentially contributing to the development of treatments for oxidative stress-related conditions.
Used in Anti-inflammatory Applications:
Harnessing its anti-inflammatory properties, (2-hydroxy-5-methoxyphenyl)(4-methylphenyl)methanone may be used in the development of drugs aimed at reducing inflammation, which could be beneficial in treating a variety of inflammatory diseases.
Used in Drug Development:
(2-hydroxy-5-methoxyphenyl)(4-methylphenyl)methanone's potential as a versatile building block in drug development makes it a candidate for creating new pharmaceuticals with diverse therapeutic applications across different medical fields.

Upstream product

• 4294-57-9 para-methylphenylmagnesium bromide 
• 2905-82-0 methyl 5-methoxy-2-hydroxybenzoate 
• 107-86-8 3,3-dimethyl acrylaldehyde 
• 42059-79-0 6-methoxy-4-oxo-4H-chromene-3-carbaldehyde 
• 104-87-0 4-methyl-benzaldehyde 
• 150-76-5 4-methoxy-phenol 
• 672-13-9 2-hydroxy-5-methoxybenzaldehyde 
• 329235-34-9 toluene-4-sulfonic acid 2-formyl-4-methoxy-phenyl ester 

Relevant academic research and scientific papers

Eco-friendly organocatalyst- And reagent-controlled selective construction of diverse and multifunctionalized 2-hydroxybenzophenone frameworks for potent UV-A/B filters by cascade benzannulation

The organocatalyst- and reagent-controlled highly selective synthesis of diversely functionalized novel 2-hydroxybenzophenone frameworks, such as 2-hydroxy-3′-formylbenzophenones, 7-(2′-hydroxybenzoyl)-2-naphthaldehydes, and 2-hydroxybenzophenones, under green conditions, for the development of potent UV-A/B filters is described. The organocatalyzed benzannulation reactions proceed individually via [3 + 3] cycloaddition for the synthesis of 2-hydroxy-3′-formylbenzophenones and [4 + 2] cycloaddition for 2-hydroxybenzophenones. With this methodology, an unprecedented double benzannulation allows one-pot construction of diverse 7-(2′-hydroxybenzoyl)-2-naphthaldehydes via [3 + 3 + 4] cycloaddition. This protocol features a broad substrate scope, high functional-group tolerance, and operational simplicity in an environmentally benign green solvent. The synthesized compounds are successfully utilized for further transformations and well characterized as potent UV-A/B filters.

Ruthenium-Catalyzed Direct Asymmetric Reductive Amination of Diaryl and Sterically Hindered Ketones with Ammonium Salts and H2

A Ru-catalyzed direct asymmetric reductive amination of ortho-OH-substituted diaryl and sterically hindered ketones with ammonium salts is reported. This method represents a straightforward route toward the synthesis of synthetically useful chiral primary diarylmethylamines and sterically hindered benzylamines (up to 97 % yield, 93–>99 % ee). Elaborations of the chiral amine products into bioactive compounds and a chiral ligand were demonstrated through manipulation of the removable and convertible -OH group.

Iridium- and rhodium-catalyzed C-H activation and formyl arylation of benzaldehydes under chelation-assistance

Mild and efficient synthesis of benzophenones via Ir(iii)- and Rh(iii)-catalyzed, directing group-assisted formyl C-H arylation of benzaldehydes has been achieved using diaryliodonium salts, in which Rh(iii) and Ir(iii) catalysts exhibited a complementary

New Methodology for the Synthesis of Xanthones

Methods are provided for forming a xanthone derivative via reacting a 2-substituted benzaldehyde with a phenol derivative to form the xanthone derivative.

Copper-catalyzed ortho-acylation of phenols with aryl aldehydes and its application in one-step preparation of xanthones

In the presence of triphenylphosphine, copper(ii) chloride can catalyze an intermolecular ortho-acylation reaction of phenols with aryl aldehydes. The reaction proceeds smoothly with a wide range of starting materials, and furthermore, it can be used to s

A concise approach to the preparation of 2-hydroxydiarylketones by an intramolecular acyl radical ipso substitution

Substituted 2-hydroxydiarylketones have been simply prepared using an intramolecular acyl radical [1,6] ipso substitution reaction. (C) 2000 Elsevier Science Ltd.