3293-32-1

Usage

Uses

Used in Pharmaceutical Industry:
2,6-di(cyclohexylidene)cyclohexan-1-one is used as a chemical intermediate for the synthesis of various pharmaceuticals. Its unique structure makes it a valuable component in the creation of new drug molecules, contributing to the development of novel treatments and medications.
Used in Flavor and Fragrance Industry:
In the flavor and fragrance industry, 2,6-di(cyclohexylide)cyclohexan-1-one is utilized to impart a sweet, floral aroma to products. Its distinct scent profile is appreciated in the formulation of perfumes, cosmetics, and other fragranced goods, enhancing the sensory experience for consumers.

InChI:InChI=1/C18H26O/c19-18-16(14-8-3-1-4-9-14)12-7-13-17(18)15-10-5-2-6-11-15/h1-13H2

Upstream product

• 1502-22-3 2-(1-cyclohexenyl)cyclohexanone 
• 108-94-1 cyclohexanone 
• 1011-12-7 2-cyclohexylidenecyclohexanone 

Downstream Products

• 1610-39-5 1,2,3,4,5,6,7,8,9,10,11,12-dodecahydrotriphenylene 
• 2432-11-3 (1,1';3',1''-terphenyl)-2'-ol 
• 20776-08-3 2-cyclohexyl-6-phenylphenol 
• 74104-10-2 4-phenyldibenzo[b,d]furan 
• 92-06-8 1,3-diphenylbenzene 
• 38320-20-6 2,6-dicyclohexyl-cyclohexanone 
• 24344-21-6 2,6-bis(1-cyclohexenyl)cyclohexanone 
• 3550-01-4 1,5,1',5'-tetraphenyl-[3,3']bicyclohexa-1,4-dienylidene-6,6'-dione 

Relevant academic research and scientific papers

The influence of the preparation method on the physico-chemical properties and catalytic activities of ce-modified ldh structures used as catalysts in condensation reactions

Mechanical activation and mechanochemical reactions are the subjects of mechanochem-istry, a special branch of chemistry studied intensively since the 19th century. Herein, we comparably describe two synthesis methods used to obtain the following layered double hydroxide doped with cerium, Mg3 Al0.75 Ce0.25 (OH)8 (CO3)0.5·2H2 O: the mechanochemical route and the co-precipitation method, respectively. The influence of the preparation method on the physico-chemical properties as determined by multiple techniques such as XRD, SEM, EDS, XPS, DRIFT, RAMAN, DR-UV-VIS, ba-sicity, acidity, real/bulk densities, and BET measurements was also analyzed. The obtained samples, abbreviated HTCe-PP (prepared by co-precipitation) and HTCe-MC (prepared by mechanochemical method), and their corresponding mixed oxides, Ce-PP (resulting from HTCe-PP) and Ce-MC (result-ing from HTCe-MC), were used as base catalysts in the self-condensation reaction of cyclohexanone and two Claisen–Schmidt condensations, which involve the reaction between an aromatic aldehyde and a ketone, at different molar ratios to synthesize compounds with significant biologic activity from the flavonoid family, namely chalcone (1,3-diphenyl-2-propen-1-one) and flavone (2-phenyl-4H-1benzoxiran-4-one). The mechanochemical route was shown to have indisputable advantages over the co-precipitation method for both the catalytic activity of the solids and the costs.

Optimization of a cyclohexanone distillation stage in the presence of alkali

Kinetics of two reactions: hydrolysis of esters and condensation of cyclohexanone in an alkaline environment, was studied in model mixtures. Derived kinetic equations were used to assess optimal parameters of proceeding cyclohexanone distillation in the presence of alkali.

METHOD FOR THE PRODUCTION OF 4,4'-[1-TRIFLUOROMETHYL)ALKYLIDENE]-BIS-(2,6-DIPHENYLPHENOLS)

The present invention relates to a process for preparing 4,4′-[1-(trifluoromethyl)alkylidene]bis(2,6-diphenylphenols), in particular for preparing 4,4′-[1-(trifluoromethyl)ethylidene]bis(2,6-diphenylphenol), which comprises the self-condensation of cyclohexanone in the presence of a basic catalyst to form tricyclic condensation products, dehydrogenation of the resulting tricyclic condensation products in the presence of a supported transition metal catalyst in the condensed phase to form 2,6-diphenylphenol and reaction of the 2,6-diphenylphenol with a trifluoromethyl ketone. The invention further provides an improved process for preparing 2,6-diphenylphenol by aldol self-condensation of cyclohexanone.

Base-catalyzed autocondensation of cyclohexanone

Autocondensation of cyclohexanone in air at 119-137°C, catalyzed with a solid alkali, was studied.