329326-35-4

Upstream product

• 329326-32-1 benzyl N-(2-(diethylphosphonyl)ethyl)-N-(thymin-1-ylacetyl)glycinate 
• 329326-33-2 N-(2-(diethylphosphonyl)ethyl)-N-(thymin-1-ylacetyl)glycine 
• 51549-36-1 N-(1-((2R,4S,5R)-5-(((tert-butyldimethylsilyl)oxy)methyl)-4-hydroxytetrahydrofuran-2-yl)-2-oxo-1,2-dihydropyrimidin-4-yl)benzamide 
• 329326-34-3 benzyl N-(2-phosphonylethyl)-N-(thymin-1-ylacetyl)glycinate 
• 20924-05-4 thymidyl acetic acid 

Downstream Products

• 329326-45-6 {(2-{[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-hydroxy-phosphoryl}-ethyl)-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-acetic acid benzyl ester 
• 329326-40-1 {(2-{[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-hydroxymethyl-tetrahydro-furan-3-yloxy]-hydroxy-phosphoryl}-ethyl)-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-acetic acid 
• 329326-39-8 {(2-{[5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yloxy]-hydroxy-phosphoryl}-ethyl)-[(5-methyl-2,4-dioxo-3,4-dihydro-2H-pyrimidin-1-yl)-acetyl]-amino}-acetic acid 

Relevant academic research and scientific papers

Synthesis and characterization of a tetranucleotide analogue containing alternating phosphonate-amide backbone linkages

Described herein is the synthesis and characterization of a tetranucleotide, 5′-dC-phosphonate-T-amide-T-phosphonate -dC (III), in which the C-T and T-C steps contain a phosphonate backbone bond and T-T is a peptide nuclei