51549-36-1

Basic information

• Product Name: N4-BENZOYL-5'-O-TERT-BUTYLDIMETHYLSILYL-2'-DEOXYCYTIDINE
• Synonyms: N4-BENZOYL-5'-O-TERT-BUTYLDIMETHYLSILYL-2'-DEOXYCYTIDINE;N-Benzoyl-5'-O-tert-butyldiMethylsilyl-2'-deoxycytidine, 98+%
• CAS NO: 51549-36-1
• Molecular Formula: C₂₂H₃₁N₃O₅Si
• Molecular Weight: 445.58
• Mol File: 51549-36-1.mol
• Article Data: 6

Chemical Properties

• Appearance: /
• CAS DataBase Reference: N4-BENZOYL-5'-O-TERT-BUTYLDIMETHYLSILYL-2'-DEOXYCYTIDINE(CAS DataBase Reference)
• NIST Chemistry Reference: N4-BENZOYL-5'-O-TERT-BUTYLDIMETHYLSILYL-2'-DEOXYCYTIDINE(51549-36-1)
• EPA Substance Registry System: N4-BENZOYL-5'-O-TERT-BUTYLDIMETHYLSILYL-2'-DEOXYCYTIDINE(51549-36-1)

Safety Data

• Hazardous Substances Data: 51549-36-1(Hazardous Substances Data)

Usage

General Description

N4-Ben-zoyl-5'-O-tert-butyldimethylsilyl-2'-deoxycytidine is a chemical compound with potential applications in the field of pharmaceuticals and biotechnology. It is a modified form of cytidine, a nucleoside that is a component of RNA and DNA. The addition of the ben-zoyl and tert-butyldimethylsilyl groups to the 5' and 2' positions, respectively, may enhance the compound's stability and pharmacokinetic properties. This modified nucleoside may be used in the development of nucleoside analogues for the treatment of viral infections and cancer, or as a probe in biological and biochemical research. Its unique structure and chemical properties make it a promising candidate for further study and potential therapeutic applications.

Upstream product

• 18162-48-6 tert-butyldimethylsilyl chloride 
• 4836-13-9 N₄-benzoyl-2'-deoxycytidine 
• 3019-98-5 pentachlorophenyl benzoate 
• 1548-84-1 pentafluorophenyl benzoate 
• 65-85-0 benzoic acid 
• 951-77-9 2'-Deoxycytidine 
• 98-88-4 benzoyl chloride 

Downstream Products

• 116872-52-7 Methyl-phosphonic acid benzotriazol-1-yl ester (2R,3S,5R)-5-(4-benzoylamino-2-oxo-2H-pyrimidin-1-yl)-2-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-3-yl ester 
• 869563-54-2 N-{1-[(2R,4S,5R)-4-[Bis-(4-methoxy-phenyl)-phenyl-methoxy]-5-(tert-butyl-dimethyl-silanyloxymethyl)-tetrahydro-furan-2-yl]-2-oxo-1,2-dihydro-pyrimidin-4-yl}-benzamide 
• 1435880-63-9 C₃₁H₄₈N₅O₆PSi 
• 1360780-24-0 C₄₄H₆₇N₉O₁₃P₂Si 
• 1360780-20-6 C₃₇H₅₁N₈O₁₂PSi 
• 1360780-19-3 C₄₅H₅₇N₈O₁₄PSi 
• 1360780-15-9 N₄-benzoyl-5'-O-tert-butyldimethylsilyl-3'-O-[(N,N-diisopropylamino)methoxyphosphino]-2'-deoxycytidine 
• 1209493-78-6 C₂₅H₃₃N₃O₅Si 
• 51549-50-9 5'-O-tert-butyldimethylsilyl-3'-O,4-N-dibenzoyl-2'-deoxycytidine 
• 116872-62-9 5'-O-t-butyldimethylsilyl N⁴-benzoyldeoxycytidine 3'-O(S-benzyl)methylphosphonothioate 

Relevant articles and documents

Pyrimidine-purine and pyrimidine heterodinucleosides synthesis containing a triazole linkage

This article describes a synthetic route to generate two purine-pyrimidine and pyrimidine heterodinucleosides. Both microwave activated regioselective alkylation using hydride and copper-catalyzed-azide-alkyne-cycloaddition (CuAAC) were used in order to perform the synthesis.

Synthesis of 3'-azido-3'-deoxythymidine-terminated oligonucleotide

A method of completely chemical synthesis of 3'-azido-3'- deoxythymidine-terminated oligonucleotides via 5'-H-phosphonate of AZT is described.

Synthesis and P-diastereomeric resolution of nucleoside 3'-O(S-alkyl) and nucleoside 3'-O(S-aryl) methylphosphonothioates

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