329358-96-5Relevant academic research and scientific papers
Exploiting polarity and chirality to probe the Hsp90 C-terminus
Forsberg, Leah K.,Davis, Rachel E.,Wimalasena, Virangika K.,Blagg, Brian S.J.
, p. 3096 - 3110 (2018)
Inhibition of the Hsp90 C-terminus is an attractive therapeutic approach for the treatment of cancer. Novobiocin, the first Hsp90 C-terminal inhibitor identified, contains a synthetically complex noviose sugar that has limited the generation of structure-
5-protected aminopyrimidine compound, production method thereof and intermediate thereof
-
Page/Page column 9, (2008/06/13)
The present invention provides a production method of 5-aminopyrimidine compound represented by the formula (5) by reacting a glycine compound represented by the formula (1) with t-butoxybisdimethylaminomethane, dimethylformamidedimethylacetal or dimethyl
