32948-96-2Relevant academic research and scientific papers
Benzo- and Indoloquinolizines. 21. Allylic Strain Competition in 4b,5,6,7,8,8a,10,11,16,16b-Decahydrodibenzindoloquinolizine Isomers. Detection of Boat Conformers by Carbon-13 Nuclear Magnetic Resonance
Tourwe, D.,Cock, E. De,Binst, G. Van
, p. 5321 - 5324 (2007/10/02)
The concept of allylic strain between the benzene or the indole ring and the benzylic carbon-carbon bond is used to explain the conformational equilibria in the 4b,5,6,7,8,8a,10,11,16,16b-decahydrodibenzindoloquinolizine isomers, in 5,6,8,9-tetrahydro-14bH-benzindoloquinolizine, and in their indole N-methyl analogues.The conformational changes were monitored by 13C chemical shifts.Boat conformers with bow-sprit-flagpole interactions between γ-positions show upfield shifts, whereas these are not observed for δ-interacting groups.
