1884-41-9

Basic information

• Product Name: 1-(cyclohex-1-en-1-yl)-3-methoxybenzene
• CAS NO: 1884-41-9
• Molecular Formula: C₁₃H₁₆O
• Molecular Weight: 188.2655
• Mol File: 1884-41-9.mol
• Article Data: 8

Chemical Properties

• Boiling Point: 296.2°C at 760 mmHg
• Flash Point: 114.9°C
• Density: 1.012g/cm³
• Vapor Pressure: 0.00257mmHg at 25°C
• Refractive Index: 1.54
• CAS DataBase Reference: 1-(cyclohex-1-en-1-yl)-3-methoxybenzene(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(cyclohex-1-en-1-yl)-3-methoxybenzene(1884-41-9)
• EPA Substance Registry System: 1-(cyclohex-1-en-1-yl)-3-methoxybenzene(1884-41-9)

Safety Data

• Hazardous Substances Data: 1884-41-9(Hazardous Substances Data)

Usage

General Description

1-(cyclohex-1-en-1-yl)-3-methoxybenzene is a chemical compound consisting of a benzene ring with a methoxy group attached at the 3-position and a cyclohexenyl group attached at the 1-position. It is a colorless liquid with a molecular formula of C13H16O and a molar mass of 188.26 g/mol. 1-(cyclohex-1-en-1-yl)-3-methoxybenzene is commonly used as a fragrance ingredient and flavoring agent in the production of perfumes, soaps, and pharmaceuticals. It is also employed in organic synthesis and chemical research as a building block for more complex organic molecules. Additionally, it is important to handle this chemical with care as it can cause skin and eye irritation and should be stored and used in a well-ventilated area with proper protective equipment.

Upstream product

• 1884-42-0 1-(m-Methoxyphenyl)cyclohexanol 
• 28075-50-5 cyclohex-1-en-1-yl trifluoromethane sulfonate 
• 38111-44-3 phenylzinc(II) bromide 
• 22524-46-5 cyclohex-1-en-1-yl 4-methylbenzenesulfonate 
• 36282-40-3 (3-methoxyphenyl)magnesium bromide 
• 108-94-1 cyclohexanone 
• 66107-33-3 3-methoxyphenyl triflate 
• 110-83-8 cyclohexene 
• 150-19-6 O-methylresorcine 
• 2398-37-0 3-methoxyphenyl bromide 
• 181705-90-8 (3-methoxyphenyl)zinc(II) bromide 

Downstream Products

• 41876-58-8 1-cyclohexyl-3-methoxybenzene 
• 105911-71-5 3-(2-nitro-cyclohex-1-enyl)-anisole 
• 93427-57-7 2-Nitro-1-m-anisyl-cyclohexen-⁽¹⁾-on-⁽⁶⁾-oxim 
• 541505-88-8 (S,S)-1-(3-Methoxy-phenyl)-7-oxa-bicyclo[4.1.0]heptane 
• 1269246-98-1 6-benzyloxy-1-(3-methoxyphenyl)cyclohexene 
• 1321159-56-1 6-(4-nitrophenylamino)-1-(3-methoxyphenyl)cyclohexene 
• 56231-51-7 3-(3-methoxyphenyl)cyclohex-2-en-1-one 
• 43050-17-5 (+/-)-1-(3-Methoxy-phenyl)-7-oxa-bicyclo[4.1.0]heptane 
• 1943-95-9 meta-cyclohexylphenol 
• 100850-47-3 3'-methoxy-4,5-dihydro-[1,1'-biphenyl]-2(3H)-one 
• 57350-39-7 (+/-)-[2t-(3-methoxy-phenyl)-3-oxo-cyclohex-r-yl]-acetic acid 

Relevant articles and documents

Synthesis of methoxetamine, its metabolites and deuterium labelled analog as analytical standards and their HPLC and chiral capillary electrophoresis separation

Methoxetamine, a designer drug marketed as a replacement for the dissociative anaesthetic ketamine, has been associated with significant numbers of hospital related intoxications and deaths in Europe. The fast and user-friendly identification and quantification of methoxetamine and its metabolites is a key factor for successful treatment of intoxication. Therefore, we suggested a convenient preparation method which was used for the synthesis of methoxetamine, seven methoxetamine metabolites and a deuterium labelled derivative as analytical standards. Methoxetamine and normethoxetamine were used as starting materials for the preparation of O-demethylated and N-dealkylated metabolites. The multistep synthesis starts from commercially available compounds and offers good yields. Our prepared analytical standards were used for the confirmation of the suggested structure of methoxetamine metabolites in rat urine by LCMS. Capillary electrophoresis was used for the chiral separation of MXE and its metabolites using β-cyclodextrin, carboxymethylated β-cyclodextrin, and sulphated β-cyclodextrin as chiral selectors at various concentrations. Chiral separation was successful for four analytes. A mixture of MXE and its metabolites was subsequently analyzed under optimal conditions, i.e. when using 15 mmol L-1 β-cyclodextrin in 50 mmol L-1 phosphate buffer, pH 2.5. In this case, chiral separation was achieved for three analytes and all analytes were separated from each other.

FeCl3/Nal-catalyzed allylic C-H oxidation of arylalkenes with a catalytic amount of disulfide under air

This paper describes a FeCl3/NaI-catalyzed formal allylic C-H oxidation of arylalkenes using a catalytic amount of disulfide with BnOH and 4-nitroaniline as nucleophiles and air as oxidant to form the corresponding allyl ethers and amines. A possible reaction mechanism has been proposed.

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