3295-92-9

Basic information

• Product Name: propan-2-yl methyl(phenyl)carbamate
• Synonyms: Carbamic acid, methylphenyl-, 1-methylethyl ester (9CI); Carbanilic acid, n-methyl, isopropyl ester
• CAS NO: 3295-92-9
• Molecular Formula: C₁₁H₁₅NO₂
• Molecular Weight: 193.2423
• Mol File: 3295-92-9.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 260.4°C at 760 mmHg
• Flash Point: 111.3°C
• Density: 1.068g/cm³
• Vapor Pressure: 0.0122mmHg at 25°C
• Refractive Index: 1.533
• CAS DataBase Reference: propan-2-yl methyl(phenyl)carbamate(CAS DataBase Reference)
• NIST Chemistry Reference: propan-2-yl methyl(phenyl)carbamate(3295-92-9)
• EPA Substance Registry System: propan-2-yl methyl(phenyl)carbamate(3295-92-9)

Safety Data

• Hazardous Substances Data: 3295-92-9(Hazardous Substances Data)

Usage

General Description

Propan-2-yl methyl(phenyl)carbamate, also known as carbaryl, is a common insecticide and pesticide utilized in agriculture and horticulture. It is a white crystalline solid with a slight characteristic odor, and is typically used to control a wide range of pests including insects, mites, and nematodes. Carbaryl works by inhibiting the action of the enzyme acetylcholinesterase, which is essential for proper nerve function in pests. This disruption in nerve function leads to paralysis and ultimately the death of the pest. Despite its effectiveness, carbaryl has been the subject of controversy due to potential human and environmental health hazards, and its use is subject to regulations in many countries.

Upstream product

• 2388-10-5 lithium isopropoxide 
• 132431-15-3 2-(N-methylanilino)-2-phenylsulfanylacetonitrile 
• 36602-08-1 (N-methylanilino)acetonitrile 
• 122-42-9 carbamic acid, phenyl-, 1-methylethyl ester 
• 74-88-4 methyl iodide 

Downstream Products

• 102992-50-7 [4-((2S,3R,4R,5S,6R)-3,4-Dihydroxy-6-hydroxymethyl-5-methoxy-tetrahydro-pyran-2-yloxy)-phenyl]-carbamic acid isopropyl ester 
• 5327-53-7 4 hydroxy Probham 
• 99985-64-5 o-methylaminobenzoate d'isopropyle 
• 122-42-9 carbamic acid, phenyl-, 1-methylethyl ester 

Relevant articles and documents

2-(N-Methylanilino)-2-phenylsulfanylacetonitrile, A Reagent Tested for Electrophilic, Nucleophilic, and Radical Reactions

2-(N-Methylanilino)-2-phenylsulfanylacetonitrile 1 has been readily prepared from 2-(N-methylanilino)acetonitrile and diphenyl disulfide.Alkylation of the anion of 1 with halogenoalkanes resulted in concurrent elimination of benzenethiol to give conjugated α-aminoalkenenitriles of 2E-configuration.Autoxidation of 1 in the presence of alkoxide ions afforded alkyl N-methyl-N-phenylcarbamates.Nucleophilic substitution of 1 with Grignard reagent or appropriate silyl compounds were promoted by CuI or Lewis acids to give varied α-amino nitriles.The 4-oxo-2-aminonitriles 9 obtained by condensation of 1 and titanium enolates can be considered as derivatives of 1,3-dicarbonyl compounds with the aldehyde group being activated to give an amino nitrile umpolung.When 1 was treated with tributylstannane, the corresponding amino nitrile α-radical was formed and the self-coupling product was isolated.

Microbial transformations. Part 4(1). Regioselective para hydroxylation of aromatic rings by the fungus Beauveria sulfurescens. The metabolism of isopropyl N-phenyl carbamate (Propham)

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