32960-67-1

Usage

Uses

Used in Organic Synthesis:
(1E)-1-(4-methoxyphenyl)cyclooctene is utilized as a key intermediate in organic synthesis for the development of new compounds. Its reactivity and structural features facilitate the creation of a wide range of chemical entities, making it a valuable component in the synthesis of complex organic molecules.
Used in Medicinal Chemistry Research:
In the field of medicinal chemistry, (1E)-1-(4-methoxyphenyl)cyclooctene serves as a versatile building block for the design and synthesis of bioactive molecules. Its potential biological activity and chemical properties make it a promising candidate for the development of pharmaceutical agents with various therapeutic applications.
Used in Pharmaceutical Industry:
(1E)-1-(4-methoxyphenyl)cyclooctene is employed as a precursor in the pharmaceutical industry for the production of drugs. Its unique structure allows for the creation of compounds with specific therapeutic effects, contributing to the advancement of new medications for the treatment of various diseases.
Used in Agrochemical Industry:
(1E)-1-(4-methoxyphenyl)cyclooctene also finds application in the agrochemical industry, where it is used as a starting material for the synthesis of agrochemicals. Its properties enable the development of new compounds with pesticidal or herbicidal activities, supporting agricultural productivity and crop protection.

Upstream product

• 931-88-4 cis-Cyclooctene 
• 696-62-8 para-iodoanisole 
• 104-92-7 1-bromo-4-methoxy-benzene 
• 502-49-8 cycloactanone 
• 86428-68-4 (E)-1-Chloro-cyclooctene 
• 5720-07-0 4-methoxyphenylboronic acid 

Relevant academic research and scientific papers

Application of a readily available and air stable monophosphine HBF4 salt for the Suzuki coupling reaction of aryl or 1-alkenyl chlorides

In this Letter, a readily available monophosphine HBF4 salt was applied for the Suzuki coupling reactions of organoboronic acids to afford the cross-coupling products in high to excellent yields. Both aryl or 1-alkenyl boronic acids and chlorides may be used. It is also suitable for sterically hindered cases.

Heck reaction of aryl halides with linear or cyclic alkenes catalysed by a tetraphosphine/palladium catalyst

cis,cis,cis-1,2,3,4-Tetrakis(diphenylphosphinomethyl)cyclopentane/[PdCl(C 3H5)]2 system catalyses efficiently the Heck reaction of aryl halides with linear alkenes such as pent-1-ene, oct-1-ene or dec-1-ene. Selectivities up to 70% in favour of E-1-arylalk-1-ene isomers can be obtained. In the presence of cyclic alkenes the selectivities of the reactions strongly depends on the ring size. Addition to cyclohexene or cycloheptene led mainly to 1-arylcycloalk-3-ene derivatives. On the other hand, addition to cyclooctene led to 1-arylcycloalk-1-ene adducts.

Ni(O) catalyzed reactions of aryl and vinyl halides with alkenes and alkynes

NI[P(OPh)3]4 and Ni[P(OET)3]4 catalyze the reaction of aryl and vinyl halides with olefins (Heck reaction) and alkynes.

Arylation of Olefins by Arylazo Aryl Sulfones under Palladium(0) Catalysis

Palladium(0)-catalyzed reaction of arylazo aryl sulfones with olefins in benzene at 80 deg C gave aryl-substituted olefins in good yield.Diarylpalladium(II) species was proposed as an intermediate in this reaction.

Process for the manufacture of new carboxylic acids

α-Phenoxyacetic acids, in which the α-position is substituted by an alkyl residue with 5 to 12 carbon atoms and the phenyl residue is substituted by a cycloaliphatic hydrocarbon residue which is unsaturated in the 1-position and is only singly unsaturated