3297-69-6

Usage

Uses

Used in Pharmaceutical Synthesis:
2-(pyridin-4-yl)cyclohexanone is used as an intermediate in the pharmaceutical industry for the synthesis of various pharmaceuticals. Its unique structure and functional groups contribute to the development of new drugs with potential therapeutic applications.
Used in Agrochemical Production:
In the agrochemical industry, 2-(pyridin-4-yl)cyclohexanone serves as a key intermediate in the production of agrochemicals. Its incorporation into these compounds can enhance their effectiveness in agricultural applications, such as pest control and crop protection.
Used in Medicinal Chemistry and Drug Discovery:
2-(pyridin-4-yl)cyclohexanone is utilized as a versatile building block in medicinal chemistry and drug discovery. Its potential applications in this field include the development of novel compounds with improved pharmacological properties, such as increased potency, selectivity, and reduced side effects.
Used for Chemical Modifications and Derivatization:
Due to its aromatic and carbonyl functional groups, 2-(pyridin-4-yl)cyclohexanone is a valuable compound for further chemical modifications and derivatization. This allows for the creation of a wide range of new compounds with diverse properties and potential applications across various industries.

Upstream product

• 110-86-1 pyridine 
• 108-94-1 cyclohexanone 
• 98-88-4 benzoyl chloride 
• 854714-97-9 2-(1-benzoyl-1,4-dihydro-[4]pyridyl)-cyclohexanone 
• 100-48-1 pyridine-4-carbonitrile 
• 931-57-7 1-methoxy-cyclohex-1-ene 
• 1424-22-2 1-cyclohexenyl acetate 
• 71831-55-5 2,6-Dimethyl-4'-(2-oxo-cyclohexyl)-4'H-[1,1']bipyridinyl-4-one 
• 7664-93-9 sulfuric acid 

Relevant academic research and scientific papers

Thioformamide derivatives

Thioformamide derivatives of formula (I): STR1 wherein R represents alkyl; A represents optionally substituted pyrid-4-yl; Y represents ethylene or methylene or a direct bond and X represents an optionally substituted phenyl, pyridyl, furyl or thienyl gro

REGIOCHEMICAL CONTROL IN THE ALLYLIC HYDROGEN ABSTRACTION FROM 1-X-SUBSTITUTED CYCLOHEXENES

Allylic hydrogen abstraction is strongly affected by substituents attached to the double bond.Evidence regarding this regiochemical control is presented for the first time.

REGIOSELECTIVE SYNTHESIS OF 4-(2-OXOALKYL)PYRIDINES VIA 1,4-DIHYDROPYRIDINE DERIVATIVES USING SILYL ENOL ETHERS AND PYRIDINIUM SALTS

Trimethylsilyl enol ethers (1) reacted with 1-ethoxycarbonylpyridinium chloride (3) at 4-position with high regioselectivity to afford 1-ethoxycarbonyl-4-(2-oxoalkyl)-1,4-dihydropyridines (4) in 42-87percent yields.When 2,2,2-trichloroethyl chloroformate

Synthetic Applications of N-N Linked Heterocycles. Part 8. Regiospecific Synthesis of 4-(α-Acylalkyl)pyridines by Attack of Lithium Enolates of Ketones γ to N-(2,6-Dimethyl-4-oxopyridin-1-yl)pyridinium Salts

The addition of N-(2,6-dimethyl-4-oxopyridin-1-yl)pyridinium salts (2) - (4) to lithium enolates (1) of ketones in tetrahydrofuran at low temperatures gives regiospecifically high yields of 1,4-dihydro-adducts (5) - (7).These are readily isolated and can be decomposed under free-radical conditions, also in high yield, to 4-(α-acylalkyl)pyridines (8) - (10).Unsymmetrical dialkyl ketones give a mixture of two isomeric products, the ratio depending upon reaction conditions and steric factors. αβ-Unsaturated ketones, however, give products resulting from reaction exclusively at the position α' to the carbonyl group.