3298-23-5Relevant academic research and scientific papers
Trimethylsilyl trifluoromethanesulfonate-promoted cyclocondensation of β-ketoenamides and subsequent nonaflation to pyrid-2-yl and pyrid-4-yl nonaflates as flexible precursors for polysubstituted pyridines
Hommes, Paul,Berlin, Sarah,Reissig, Hans-Ulrich
, p. 3288 - 3294 (2013/12/04)
The intramolecular condensation of β-ketoenamides to 2- and/or 4-pyridone derivatives using either KOt-Bu or trimethylsilyl trifluoromethanesulfonate/Hu?nig's base was investigated. Subsequent nonaflation of the cyclization products allowed a facile purification and further functionalization through Suzuki-Miyaura couplings leading to new highly substituted pyridine derivatives. The dependence of the regioselectivity of cyclocondensation on the structure of the β-ketoenamides is discussed. Georg Thieme Verlag Stuttgart New York.
Heterocycles. Part V . Reaction of α,β-Unsaturated Carbonyl Compounds with Arylacetamides. A Synthesis of 2-Pyridone Derivatives
El-Rayyes, N. R.,Al-Hajjar, F. H.
, p. 1473 - 1477 (2007/10/02)
The reaction of 1,3-diaryl-2-propene-1-ones I with arylacetamides II, in the presence of sodium ethoxide under reflux, for two hours, gave the corresponding 3,4,6-triaryl-3,4-dihydro-2(1H)-pyridones IV.However, when the reaction of these ketones was carri
Pyrazines. Part 5. Preparation of 3,8-Diazabicyclooctane-2,4-dione Derivatives
Cartoon, Maureen E. K.,Cheeseman, Gordon W. H.,Dowlatshahi, Hossein,Sharma, Rramila
, p. 1603 - 1606 (2007/10/02)
The title compounds were formed by cycloaddition of 2,6-dihydroxy-3,5-diphenylpyrazine to acetylenes and electron-deficient olefins.
