3299-24-9

Usage

Uses

Used in Pharmaceutical Industry:
Fluoroformic acid trifluoromethyl ester is used as a reagent in organic synthesis processes for its ability to transfer the trifluoromethyl group to other molecules, which is crucial in the development of various pharmaceutical compounds.
Used in Agrochemical Industry:
Similarly, in the agrochemical industry, fluoroformic acid trifluoromethyl ester serves as a reagent for the synthesis of agrochemicals, contributing to the creation of effective pesticides and other agricultural products.
Used as a Solvent:
Fluoroformic acid trifluoromethyl ester is also used as a solvent in certain chemical processes due to its unique properties, providing a medium for reactions to occur.
Used in the Production of Fluorinated Materials:
Fluoroformic acid trifluoromethyl ester is utilized as a precursor in the production of fluorinated materials, which have a wide range of applications across various industries, including electronics and materials science.
Safety Measures:
Due to its potential health hazards and environmental impact, the use and handling of fluoroformic acid trifluoromethyl ester should be conducted with proper safety measures and precautions to mitigate risks.

Upstream product

• 373-91-1 hypofluorous acid trifluoromethyl ester 
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• 2070-70-4 perfluoro-4-methyl-2-pentene 

Relevant academic research and scientific papers

Kinetics and mechanism of the thermal gas-phase oxidation of perfluorobutene-2 in presence of trifluoromethyl hypofluorite

The oxidation of perfluorobutene-2 (C4F8) initiated by trifluoromethyl hypofluorite (CF3OF) in presence of O2 has been studied at 323.1, 332.6, 342.5, and 352.0 K, using a conventional static system. The initial pressure of CF3OF was varied between 4.8 and 23.6 Torr, that of C4F8 between 48.7 and 302.4 Torr, and that of O2 between 51.5 and 270.4 Torr. Several runs were made in presence of 325.5-451.2 Torr of N2. The main products were COF2, CF3C(O)F, and CF3OC(O)F. Small amounts of compound containing -CF(CF3)-O-C(O)CF3 group were also formed, as detected by 13C NMR spectroscopy. The oxidation is a homogeneous short-chain reaction, attaining, at the pressure of O2 used, the pseudo-zero-order condition with respect to O2 as reactant. The reaction is independent of the total pressure. Its basic steps are as follows: the thermal generation of CF3O radicals by the abstraction of fluorine atom of CF3OF by C4F8, the addition of CF3O to the alkene, the formation of perfluoroalkoxy radicals RO in presence of O2, and the decomposition of these radicals via the C-C bond scission, giving products containing -C(O)F end group and reforming RO and CF3O radicals. The mechanism consistent with experimental results is postulated.

Synthesis of trifluoromethyl fluoroformate from trifluoromethyl hypofluorite and carbon monoxide: Thermal and catalyzed reaction

New and improved routes to trifluoromethyl fluoroformate were developed. Sterically hindered halogenated olefins initiated the reaction of CF3OF and CO under mild conditions, giving yields of up to 80%. The thermal reaction of CF3OF

TFE-based thermoprocessable copolymers

TFE-based thermoprocessable copolymers having the following composition, expressed in percentage by moles on the total of the monomers: A) from 0.01 to 15% of the monomer of formula: [in-line-formulae]CF2═CFOCF2OCF3??(a); [/in-line-formulae] A1) tetrafluoroethylene from 99.99 to 85%; optionally B) one or more (per)fluorinated comonomers having at least one unsaturation of ethylene type, different from TFE; the sum of the molar percentages A)+B) being such as to give polymers showing at least one melting peak at the thermogravimetric analysis (DSC).

Kinetics and mechanism of thermal gas-phase oxidation of hexafluoropropene in the presence of trifluoromethylhypofluorite, CF3OF

The oxidation of hexafluoropropene with molecular oxygen in the presence of CF3OF has been studied at 303.0, 313.0 and 323.4 K, using a conventional static system. The initial pressure of CF3OF was varied between 1.7 and 16.6 Torr, that of C3F6 between 10.0 and 120.2 Torr and that of O2 between 82.0 and 599.8 Torr. Several runs were made in the presence of 325.3-499.2 Torr of N2. Major products were COF2, CF3C(O)F, CF3OC(O)F and a new compound, CF3OCF2OCF2C(O)F. The latter was characterised by the determination of its relative molecular mass and its IR spectrum, which is consistent with the calculated one using theoretical approximations. Small amounts of CF3OCF2C(O)F were also formed. The oxidation is an homogeneous chain reaction, attaining, at the pressure of O2 used, the pseudo-zero-order condition with respect to O2 as a reactant. It is independent of the total pressure. The basic steps are: the thermal generation of CF3O radicals by abstraction of the fluorine atom from CF3OF by C3F6, chain initiation by the addition of CF3O to olefin leading, in the presence of O2, to the formation of haloalkoxy radicals, which decompose via the C-C scission to give products containing C(O)F group and CF3 radicals, reforming CF3O. The full mechanism is postulated.

Kinetics and Mechanism of the Thermal Reaction between Perfluorobutene-2 and Trifluoromethylhypofluorite

The kinetics of the thermal reaction between CF3OF and C4F8 have been investigated in the range of 30 deg C to 90 deg C.It was found to be a homogeneous chain reaction of moderate length.The main product is CF3CF(OCF3)CF2CF3, accompanied by small amounts of C8F18, CF3OOCF3 and CF3CF(OCF3)CF(OCF3)CF3 in constant ratio.Traces of (CF3CF(OCF3)CFCF3)2 are also formed.Inert gases and reaction products have no influence on the reaction, whereas small amounts of oxygen change its course.Under conditions in which / > 1, the reaction follows a second order rate expressi on - = k.The following mechanism explains the experimental results .The chain length ν = /2 is found to be ν = 19+/-3 in the range 32 deg C to 92 deg C, the rate constant of the starting reaction k1 = (5.34+/-0.30)106exp(-13.9 kcal*mol-1/RT)l*mol-1*s-1. - Keywords: Kinetics / Thermal reaction / Perfluorobutene-2 / Trifluoromethylhypofluorite / Perfluoroalkyl radicals