329956-49-2Relevant academic research and scientific papers
Synthesis of chiral pyrrolidine and pyrrole derivatives through the chemoselective Dieckmann reaction of α,β-aminodiesters
Pinto, Americo C.,Abdala, Rodrigo V.,Costa, Paulo R.R.
, p. 4239 - 4243 (2007/10/03)
α,β-Aminodiesters were allowed to react with t-BuOK in THF at -78°C. The chemoselectivity of the Dieckmann cyclization was controlled by the nature of the substituents R3 and R4, allowing the preparation of pyrrolidine or pyrrole derivatives. (C) 2000 Elsevier Science Ltd.
