32999-10-3

Upstream product

• 4426-47-5 butylboronic acid 
• 120-80-9 benzene-1,2-diol 
• 14090-22-3 butyl-dichloro-borane 
• 13826-27-2 2,2'-bis(1,3,2-benzodioxaborole) 
• 109-72-8 n-butyllithium 
• 51901-85-0 bromocatecholborane 
• 4887-12-1 1,2-di-n-butyl-1,2-bis(dimethylamino) diborane 
• 106-98-9 1-butylene 
• 274-07-7 benzo[1,3,2]dioxaborole 
• 37737-62-5 tris(catecholato)diboron 

Downstream Products

• 4426-47-5 butylboronic acid 
• 69190-62-1 pinacol butylboronate 
• 583-03-9 1-Phenyl-1-pentanol 

Relevant academic research and scientific papers

Light-Mediated Sulfur-Boron Exchange

Interaction of sulfides bearing a tetrafluoropyridinyl group with bis(catecholato)diboron followed by treatment with pinacol and triethylamine affording pinacol boronic esters is described. The reaction is promoted by an organic photocatalyst (3DPA2FBN) u

Urushiol detection using a profluorescent nitroxide

A method to visually detect minute amounts of urushiol, the toxic catechol from poison oak, poison ivy, and poison sumac, has been developed utilizing the reaction of a profluorescent nitroxide with the B-n-butylcatecholboronate ester formed in situ from urushiol and B-n-butylboronic acid. The resulting N-alkoxyamine is strongly fluorescent upon illumination with a fluorescent lamp, allowing the location of the toxic urushiol contamination to be visualized. This methodology constitutes the groundwork for the future development of a spray to detect urushiol to avoid contact dermatitis, as well as to detect catecholamines for biomedical applications.

FLUORESCENCE DETECTION OF POISON OAK OIL

The invention herein disclosed provides for compositions, methods for synthesizing said compositions, and methods for using said compositions, wherein the compositions and methods may be used to bind to and/or deactivate a poison oak oil, such as urushiol. The compositions and methods can be used to treat and/or reduce an inflammatory reaction and/or hypersensitivity to natural compounds found in poison oak, poison ivy, poison sumac, mango, lac tree, and cashew nut.

Synthesis of 4-alkyl-3-bromo-2(5H)-furanones and unsymmetrically disubstituted 3,4-dialkyl-2(5H)-furanones by palladium-catalyzed cross-coupling reactions

Easily available 3,4-dibromo-2(5H)-furanone undergoes a regioselective cross-coupling reaction with alkylboronic acids in the presence of catalytic amounts of PdCl2(MeCN)2 and AsPh3 and a large molar excess of Ag2O to provide the corresponding 4-alkyl-3-bromo-2(5H)-furanones in satisfactory yields. These monobromo derivatives have proven to be useful precursors to unsymmetrically substituted 3,4-dialkyl-2(5H)-furanones which include the racemic form of naturally occurring seiridin.