32999-75-0Relevant academic research and scientific papers
Diastereoselective addition of organozinc reagents to chiral α-imino esters
Chiev, Kan Pa,Roland, Sylvain,Mangeney, Pierre
, p. 2205 - 2209 (2002)
The addition of organozinc reagents to chiral α-imino esters pre-complexed with zinc bromide, occurred with complete regioselectivity at the imino carbon. The influence of the solvent, temperature and different chiral auxiliaries was studied. The best diastereoselectivities were obtained in Et2O or CH2Cl2 at 0°C, using phenylglycinol methyl ether as the chiral inductor.
