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Benzenamine, 3,5-difluoro-N-phenyl-, also known as 3,5-difluoro-N-phenylaniline or 3,5-difluoro-N-phenylbenzenamine, is an organic compound with the chemical formula C12H8F2N. It is a derivative of aniline, where two hydrogen atoms on the benzene ring are replaced by fluorine atoms, and another benzene ring is attached to the nitrogen atom. Benzenamine,3,5-difluoro-N-phenyl- is characterized by its unique electronic properties due to the presence of fluorine atoms, which can influence its reactivity and stability. It is used in the synthesis of various pharmaceuticals, agrochemicals, and other specialty chemicals, taking advantage of its specific chemical reactivity and the ability to form different types of chemical bonds. The compound is typically synthesized through various chemical reactions, such as the Friedel-Crafts acylation or nucleophilic substitution, and is an important building block in the development of new molecules with potential applications in various industries.

330-31-4

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330-31-4 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 330-31-4 includes 6 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 3 digits, 3,3 and 0 respectively; the second part has 2 digits, 3 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 330-31:
(5*3)+(4*3)+(3*0)+(2*3)+(1*1)=34
34 % 10 = 4
So 330-31-4 is a valid CAS Registry Number.

330-31-4SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 3,5-difluoro-N-phenylaniline

1.2 Other means of identification

Product number -
Other names -

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:330-31-4 SDS

330-31-4Downstream Products

330-31-4Relevant academic research and scientific papers

PROSTACYCLIN RECEPTOR AGONIST

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Paragraph 0088-0090; 0140-0142, (2020/12/22)

A compound represented by formula (I) or an isomer or a pharmaceutically acceptable salt thereof. The present invention also relates to an application of the same in preparing a drug for treating a disease related to a PGI2 receptor.

Effective, transition metal free and selective C-F activation under mild conditions

Kong, Xianqiang,Zhang, Huizi,Xiao, Yunqing,Cao, Changsheng,Shi, Yanhui,Pang, Guangsheng

, p. 7035 - 7048 (2015/03/03)

A simple and effective aromatic nucleophilic monosubstitution reaction for the synthesis of aromatic amines via selective C-F bond cleavage of various fluoroarenes (mono-, di-, tri-, tetra-, penta- and perfluorobenzene) with primary and secondary aromatic amines under transition metal free conditions is demonstrated. The reaction conditions were investigated thoroughly for a wide range of fluoroarene substrates bearing different numbers of fluorine atoms, and the results showed that the solvent and reaction temperature are very crucial for the successful substitution reactions. The established methods enabled the formation of nonfluorinated and partially fluorinated aromatic amines in good to excellent yields. Several functional groups were tolerated under the optimized conditions.

MODULATORS OF THE PROSTACYCLIN (PGI2) RECEPTOR USEFUL FOR THE TREATMENT OF DISORDERS RELATED THERETO

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Page/Page column 158, (2009/10/22)

The present invention relates to amide derivatives of Formula (XIIIa) and pharmaceutical compositions thereof that modulate the activity of the PGI2 receptor. Compounds of the present invention and pharmaceutical compositions thereof are directed to metho

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