33012-76-9

Usage

Molecular structure

Pyrrolidine ring and acetic acid side chain The compound features a pyrrolidine ring, which is a five-membered nitrogen-containing ring, and an acetic acid side chain, which is a methyl group connected to a carboxyl group.

Optical activity

(S)-(9CI) designation The (S)-(9CI) designation indicates that the compound is optically active, meaning it can rotate plane-polarized light. This implies that the compound has a specific three-dimensional arrangement of atoms, or chirality, which affects its interactions with other molecules.

Pharmaceutical potential

Structural features and biological interactions Due to its unique structure, 1-Pyrrolidineacetic acid, 2-carboxy-, (S)-(9CI) may have potential pharmaceutical applications, as it could interact with biological systems in various ways.

Safety precautions

Potential biological activity and risks It is crucial to handle this chemical compound with care and follow proper safety protocols, as it may have potential biological activity and could pose risks if mishandled.

Upstream product

• 79-08-3 bromoacetic acid 
• 147-85-3 L-proline 
• 79-11-8 chloroacetic acid 

Relevant academic research and scientific papers

Ternary copper(II) complexes with N-carboxymethyl-l-prolinato(2-) ion and imidazole or creatinine: A comparative study of the interligand interactions influencing the molecular recognition and stability

The compounds {[Cu(CMP)(Him)]·H2O}n (I) and [Cu(CMP)(crea)H2O]·3H2O (II) were synthesized and characterized by X-ray diffraction, thermal, spectral and magnetic methods (CMP = N-carboxymethyl-;l-prolinato(2-) ion, Him = imidazole and crea = creatinine). Appropriate structural comparison with other compounds such as {[Cu(CMP)(H2O)]·H2O}n, [Cu(crea)2Cl2] and [Cu(dipeptide)(crea)(H2O)x]·nH2O (x = 0 or 1) have been made in order to prove that crea can act as an imidazole-like ligand (because it is able to promote the same fac- to mer-CMP tridentate conformational change in copper(II) complexes) as well as to discuss the interligand interactions which control the 'Cu(CMP) complex-crea, molecular recognition processes. In contrast to that found in related ternary complexes, we have concluded that direct CMP-crea interligand interactions are missing in the Cu-CMP-crea complex due to the inappropriate correspondence between the donor and/or acceptor H-bonding properties of these ligands. CMP can only act as H-acceptor by its two terminal carboxylate group, and crea can display H-donor and H-acceptor roles by its exocyclic -NH2 and O moieties, respectively. That promotes the reinforcement of the Cu-N(crea) bond by a bridge -N-H(crea)...O(aqua) (2.867(3) ?, 176.4°).