33018-91-6

Basic information

• Product Name: BOC-HIS(TOS)-MERRIFIELD RESIN
• Synonyms: ethyl hydrogen heptane-1,7-dioate;Monoethyl Heptanedioate;heptanedioic acid monoethyl ester;Pimelic acid monomethyl ester;Heptanedioic acid 1-ethyl ester;Pimelic acid 1-hydrogen 7-ethyl ester;N-Alpha-T-Butoxycarbonyl-N-Im-Tosyl-L-Histidine-P-Hydroxymethyl Phenylacet;Ethyl hydrogen pimelate
• CAS NO: 33018-91-6
• Molecular Formula: C₉H₁₆O₄
• Molecular Weight: 188.22
• EINECS: 251-346-6
• Product Categories: Miscellaneous
• Mol File: 33018-91-6.mol
• Article Data: 5

Chemical Properties

• Melting Point: 10°C
• Boiling Point: 135-138°C 1mm
• Flash Point: 135-138°C/1mm
• Appearance: /
• Density: 1.06
• Vapor Pressure: 0.000581mmHg at 25°C
• Refractive Index: 1.4420
• Storage Temp.: 2-8°C
• PKA: 4.74±0.10(Predicted)
• Water Solubility: Not miscible or difficult to mix with water.
• BRN: 1774583
• CAS DataBase Reference: BOC-HIS(TOS)-MERRIFIELD RESIN(CAS DataBase Reference)
• NIST Chemistry Reference: BOC-HIS(TOS)-MERRIFIELD RESIN(33018-91-6)
• EPA Substance Registry System: BOC-HIS(TOS)-MERRIFIELD RESIN(33018-91-6)

Safety Data

• Statements: 36/38
• Safety Statements: 26-36
• WGK Germany: 3
• Hazardous Substances Data: 33018-91-6(Hazardous Substances Data)

Usage

Uses

Ethyl hydrogen pimelate is an important raw material and intermediate used in organic synthesis, pharmaceuticals, agrochemicals and dyestuff fields.

InChI:InChI=1/C9H16O4/c1-2-13-9(12)7-5-3-4-6-8(10)11/h2-7H2,1H3,(H,10,11)

Upstream product

• 111-16-0 heptanedioic acid 
• 2050-20-6 diethyl pimelate 
• 64-17-5 ethanol 
• 142-79-0 pimeloyl chloride 

Downstream Products

• 103187-20-8 7-Hydroxy-7-(4-methoxy-phenyl)-heptanoic acid 
• 875771-79-2 C₁₈H₂₄O₆ 

Relevant articles and documents

Novel Myocyte Enhancer Factor 2 (MEF2) modulators

The present disclosure provides novel compounds capable of functioning as Myoctye Enhancer Factor 2 (MEF2) modulators, as well as compositions, pharmaceutical formulations, methods of synthesis and kits. Also provided are methods of treating a condition regulatable by MEF2 and/or MEF2 cofactors using the compounds, compositions, pharmaceutical formulations, and kits provided herein.

NOVEL TRANSCRIPTION FACTOR MODULATORS

The present disclosure provides novel compounds capable of functioning as transcription factor modulators, as well as compositions, pharmaceutical formulations, and kits. Also provided are methods of treating a condition regulatable by a transcription factor and/or cofactor using the compounds, compositions, pharmaceutical formulations, and kits provided herein.

The synthesis of the vitamers of biotin

An efficient synthetic pathway for the preparation of the vitamers of biotin which provides easy access to optically pure KAPA as well as diastereomeric mixtures of DAPA, DTB, and analogs thereof has been developed.