330195-73-8Relevant academic research and scientific papers
Synthesis of analogs of wasabi phytoalexin (methyl 1-methoxyindole-3-carboxylate)
Yamada, Koji,Kanbayashi, Yukiko,Tomioka, Saori,Somei, Masanori
, p. 1627 - 1634 (2007/10/03)
Syntheses of wasabi phytoalexin analogs, such as 6-bromo-5-iodo, 2-bromo-5-iodo, 6-nitro, 5-chloroacetyl, and 6-chloroacetyl congeners, are reported. An interesting effect of the 1-methoxy group on the regioselectivity of electrophilic substitution reactions on indole nucleus is observed.
Syntheses of wasabi phytoalexin (methyl 1-methoxyindole-3-carboxylate) and its 5-iodo derivative, and their nucleophilic substitution reactions
Somei, Masanori,Tanimoto, Asuka,Orita, Hitomi,Yamada, Fumio,Ohta, Toshiharu
, p. 425 - 432 (2007/10/03)
A simple synthetic method for methyl 1-methoxyindole-3-carboxylate, a phytoalexin isolated from Wasabia japonica, syn. Eutrema wasabi, and its 5-iodo derivative is reported. They underwent nucleophilic substitution reactions selectively at the 2-position.
