Basic information

Product Name: 1-(2-chloroethyl)-1-nitroso-3-(2,4,6-trimethylphenyl)urea
Synonyms: 1-(2-Chloroethyl)-3-mesityl-1-nitrosourea; urea, N-(2-chloroethyl)-N-nitroso-N'-(2,4,6-trimethylphenyl)-
CAS NO:33022-06-9
Molecular Formula: C₁₂H₁₆ClN₃O₂
Molecular Weight: 269.7273
EINECS: N/A
Product Categories: N/A

Chemical Properties

Melting Point: N/A
Boiling Point: N/A
Flash Point: N/A
Appearance: N/A
Density: 1.23g/cm³
Refractive Index: 1.563
Storage Temp.: N/A
Solubility: N/A
CAS DataBase Reference: 1-(2-chloroethyl)-1-nitroso-3-(2,4,6-trimethylphenyl)urea(CAS DataBase Reference)
NIST Chemistry Reference: 1-(2-chloroethyl)-1-nitroso-3-(2,4,6-trimethylphenyl)urea(33022-06-9)
EPA Substance Registry System: 1-(2-chloroethyl)-1-nitroso-3-(2,4,6-trimethylphenyl)urea(33022-06-9)

Safety Data

Hazard Codes: N/A
Statements: N/A
Safety Statements: N/A
WGK Germany:
RTECS:
HazardClass: N/A
PackingGroup: N/A
Hazardous Substances Data: 33022-06-9(Hazardous Substances Data)

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33022-06-9 Usage

Uses

Used in Oncology:
Nimustine is used as a chemotherapy agent for the treatment of various types of cancer, including brain tumors and lung cancer. Its application is based on its mechanism of action, which involves inducing DNA damage and interfering with DNA synthesis, leading to the inhibition of cancer cell growth.
Used in Pharmaceutical Industry:
In the pharmaceutical industry, Nimustine is utilized as an active pharmaceutical ingredient in the development of cancer treatments. Its ability to cross the blood-brain barrier makes it a unique and important compound for the creation of drugs targeting brain tumors.
However, it is important to note that Nimustine can cause side effects such as myelosuppression, nausea, and vomiting, which must be carefully managed in clinical settings. Despite these side effects, Nimustine remains a significant and effective anticancer agent with potential therapeutic benefits for a range of cancer types.

Check Digit Verification of cas no

The CAS Registry Mumber 33022-06-9 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,0,2 and 2 respectively; the second part has 2 digits, 0 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 33022-06:
(7*3)+(6*3)+(5*0)+(4*2)+(3*2)+(2*0)+(1*6)=59
59 % 10 = 9
So 33022-06-9 is a valid CAS Registry Number.

33022-06-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name	1-(2-chloroethyl)-1-nitroso-3-(2,4,6-trimethylphenyl)urea

1.2 Other means of identification

Product number	-
Other names	Urea, N-(2-chloroethyl)-N-nitroso-N‘-(2,4,6-trimethylphenyl)-

1.3 Recommended use of the chemical and restrictions on use

Identified uses	For industry use only.
Uses advised against	no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number	-
Service hours	Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33022-06-9 SDS

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