33044-74-5 Usage
Uses
Used in Pharmaceutical Industry:
(2R)-3,3aβ,4,5-Tetrahydro-3β-hydroxy-2,5,5-trimethyl-2α,4α-ethano-2H,9H-dipyrano[4,3,2-de:3',2'-g][1]benzopyran-9-one is used as a potential therapeutic agent for various conditions due to its antioxidant and anti-inflammatory properties. Its unique structure and chiral nature make it a promising candidate for the development of new drugs targeting a range of diseases.
Used in Research:
(2R)-3,3aβ,4,5-Tetrahydro-3β-hydroxy-2,5,5-trimethyl-2α,4α-ethano-2H,9H-dipyrano[4,3,2-de:3',2'-g][1]benzopyran-9-one is used as a subject of study in chemical and biological research to better understand its properties, potential applications, and interactions with biological systems. Its complex structure and chiral nature provide valuable insights into the development of new compounds and therapeutic strategies.
Check Digit Verification of cas no
The CAS Registry Mumber 33044-74-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,0,4 and 4 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 33044-74:
(7*3)+(6*3)+(5*0)+(4*4)+(3*4)+(2*7)+(1*4)=85
85 % 10 = 5
So 33044-74-5 is a valid CAS Registry Number.
InChI:InChI=1/C19H20O5/c1-18(2)10-6-7-19(3)17(21)14(10)15-12(23-18)8-11-9(16(15)24-19)4-5-13(20)22-11/h4-5,8,10,14,17,21H,6-7H2,1-3H3
33044-74-5Relevant academic research and scientific papers
Biomimetic Synthetic Studies on the Bruceol Family of Meroterpenoid Natural Products
Day, Aaron J.,George, Jonathan H.,Sumby, Christopher J.
, (2020/02/04)
A biomimetic approach to total synthesis can offer several benefits, including the development of cascade reactions for the rapid generation of molecular complexity, and guidance in the structure revision of old natural products and the anticipation of ne
Biomimetic and Biocatalytic Synthesis of Bruceol
Day, Aaron J.,Lee, Joel H. Z.,Phan, Quang D.,Lam, Hiu C.,Ametovski, Adam,Sumby, Christopher J.,Bell, Stephen G.,George, Jonathan H.
supporting information, p. 1427 - 1431 (2019/01/05)
The first total synthesis of bruceol has been achieved using a biomimetic cascade cyclization initiated by a stereoselective Jacobsen–Katsuki epoxidation (and kinetic resolution) of racemic protobruceol-I. A bacterial cytochrome P450 monooxygenase was also found to catalyze the conversion of protobruceol-I into bruceol. The first full analysis of the NMR data of natural bruceol suggested that “isobruceol” was a previously unrecognized natural product also isolated from Philotheca brucei. This was confirmed by the re-isolation, synthesis, and X-ray analysis of isobruceol. In total, eight stereoisomers and structural isomers of bruceol have been synthesized in a highly divergent approach.
