33046-20-7

Upstream product

• 765-47-9 1,2-dimethylcyclopentene 
• 917-64-6 methyl magnesium iodide 
• 89489-58-7 methyl 1-hydroxycyclobutanecarboxylate 
• 3721-95-7 Cyclobutanecarboxylic acid 
• 41248-13-9 1-hydroxycyclobutane-1-carboxylic acid 

Downstream Products

• 4541-32-6 2,2-dimethylcyclopentanone 
• 13505-34-5 2,6-heptandione 

Relevant academic research and scientific papers

Gas-Phase Reactions of 1,2-Dimethylcyclopentene and of 2,6-Heptanedione with Ozone: Unprecedented Formation of an Ozonide by Ozone Treatment of a Diketone

Gas-phase ozonizations of 1,2-dimethylcyclopentene (1) and of 2,6-heptanedione (5) afforded in each case dimethylcyclopentene ozonide (2) in low yields. In the ozonization of 1, diketone 5 was formed as the single major product, along with nine "abnormal" ozonolysis products which were formed by oxidative cleavage of carbon-carbon single bonds.

Regioselective synthesis of α,α-dialkylcyclopentanones from 1-hydroxycyclobutanecarboxylic acid or from O-protected cyclobutanone cyanohydrin

1-(1-Hydroxyalkyl)cyclobutanols 4a-f, readily available either from 1-hydroxycyclobutane carboxylic acid or from O-protected cyclobutanone cyanohydrin, appeared the most suitable precursors for a regioselective synthesis of cyclopentanones α,α- disubstituted with various similar or different alkyl, alkenyl, aryl or cycloalkyl groups. The key steps consist of acid or Grignard reagent induced C4→C5 ring expansions.