330583-66-9

Basic information

• Product Name: (2S,4R)-2-(Benzyl-methyl-carbamoyl)-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester
• Synonyms: (2S,4R)-2-(Benzyl-methyl-carbamoyl)-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester
• CAS NO: 330583-66-9
• Molecular Weight: 334.415
• Mol File: 330583-66-9.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (2S,4R)-2-(Benzyl-methyl-carbamoyl)-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: (2S,4R)-2-(Benzyl-methyl-carbamoyl)-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester(330583-66-9)
• EPA Substance Registry System: (2S,4R)-2-(Benzyl-methyl-carbamoyl)-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester(330583-66-9)

Safety Data

• Hazardous Substances Data: 330583-66-9(Hazardous Substances Data)

Upstream product

• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 
• 103-67-3 benzyl-methyl-amine 

Downstream Products

• 330583-68-1 ((2S,4R)-4-Allyloxy-1-methyl-pyrrolidin-2-ylmethyl)-benzyl-methyl-amine 
• 330583-67-0 (3R,5S)-5-[(Benzyl-methyl-amino)-methyl]-1-methyl-pyrrolidin-3-ol 

Relevant articles and documents

A polymer-supported proline-based diamine catalyst for the kinetic resolution of racemic secondary alcohols

The preparation of polymer-supported proline-based diamine catalyst 12 for the kinetic resolution of racemic mixtures of secondary alcohols is described. Not only is the catalyst effective for the resolution of a host of different alcohols, it can also be recovered and reused several times without loss of either activity or selectivity. The catalyst has been used in conjunction with a polymer-supported sequestration strategy, giving rise to an essentially pure mixture of resolved products that can be separated using flash chromatography.