330583-67-0

Upstream product

• 103-67-3 benzyl-methyl-amine 
• 13726-69-7 (2S,4R)-4-hydroxy-1-[(2-methylpropan-2-yl)oxycarbonyl]pyrrolidine-2-carboxylic acid 
• 330583-66-9 (2S,4R)-2-(Benzyl-methyl-carbamoyl)-4-hydroxy-pyrrolidine-1-carboxylic acid tert-butyl ester 

Downstream Products

• 330583-68-1 ((2S,4R)-4-Allyloxy-1-methyl-pyrrolidin-2-ylmethyl)-benzyl-methyl-amine 

Relevant academic research and scientific papers

A polymer-supported proline-based diamine catalyst for the kinetic resolution of racemic secondary alcohols

The preparation of polymer-supported proline-based diamine catalyst 12 for the kinetic resolution of racemic mixtures of secondary alcohols is described. Not only is the catalyst effective for the resolution of a host of different alcohols, it can also be recovered and reused several times without loss of either activity or selectivity. The catalyst has been used in conjunction with a polymer-supported sequestration strategy, giving rise to an essentially pure mixture of resolved products that can be separated using flash chromatography.