3306-29-4

Basic information

• Product Name: 3,4-DIMETHOXY-3,5,7-TRIHYDROXYFLAVONE
• Synonyms: DILLENETIN;3,4-DIMETHOXY-3,5,7-TRIHYDROXYFLAVONE;QUERCETIN-3',4'-DIMETHYL ETHER;3',4'-Di-O-Methylquercetin;3-O-Methyltamarixetin;Desmethoxycentaureidin;Tamarixetin 3-methylether
• CAS NO: 3306-29-4
• Molecular Formula: C₁₇H₁₄O₇
• Molecular Weight: 330.29
• Product Categories: Flavones
• Mol File: 3306-29-4.mol
• Article Data: 4

Chemical Properties

• Boiling Point: 562.2°Cat760mmHg
• Flash Point: 209.5°C
• Appearance: /
• Density: 1.507g/cm³
• Vapor Pressure: 3.02E-13mmHg at 25°C
• Refractive Index: 1.681
• CAS DataBase Reference: 3,4-DIMETHOXY-3,5,7-TRIHYDROXYFLAVONE(CAS DataBase Reference)
• NIST Chemistry Reference: 3,4-DIMETHOXY-3,5,7-TRIHYDROXYFLAVONE(3306-29-4)
• EPA Substance Registry System: 3,4-DIMETHOXY-3,5,7-TRIHYDROXYFLAVONE(3306-29-4)

Safety Data

• Hazardous Substances Data: 3306-29-4(Hazardous Substances Data)

Usage

InChI:InChI=1/C17H14O7/c1-22-11-4-3-8(5-12(11)23-2)17-16(21)15(20)14-10(19)6-9(18)7-13(14)24-17/h3-7,18-19,21H,1-2H3

Upstream product

• 117-39-5 quercetol 
• 485-80-3 S-adenosyl-L-methionine 
• 1393953-75-7 2-(3,4-dimethoxyphenyl)-5-hydroxy-3,7-bis(methoxymethoxy)-4H-chromen-4-one 

Relevant articles and documents

A new flavonol glycoside from the aerial part of Alhagi pseudalhagi

The new flavonol glycoside alhaoside was isolated from the aerial part of Alhagi pseudalhagi (Fabaceae). The structure 3,4-di-O-methylquercetin-3-O- α-L-rhamnopyranosyl-(1→6)-β-D-glucopyranosyl-7-O-α- Lrhamnopyranosyl-(1→6)-β-D-galactopyranoside was established for alhaoside based on spectral characteristics and chemical transformations.

Biological evaluation and SAR analysis of O-methylated analogs of quercetin as inhibitors of cancer cell proliferation

Preclinical Research Using a high-throughout screening approach, the anticancer activities of 16 O-methylated (OMe) analogs of quercetin were assessed. The structure-activity relationships showed that OMe moieties at the 4′ and/or 7 positions were important for maintaining inhibitory activities against the 16 cancer cell lines. Furthermore, when the OH groups at the 3′ and 4′ positions were both replaced by OMe moieties, anticancer activity was enhanced.