33061-24-4

Basic information

• Product Name: 2-(Dimethylamino)-3',4'-dimethoxyacetophenone
• Synonyms: 2-(Dimethylamino)-3',4'-dimethoxyacetophenone
• CAS NO: 33061-24-4
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.26828
• Mol File: 33061-24-4.mol
• Article Data: 4

Chemical Properties

• Melting Point: 98-100 °C
• Boiling Point: 330.8°Cat760mmHg
• Flash Point: 153.9°C
• Appearance: /
• Density: 1.067g/cm³
• Vapor Pressure: 0mmHg at 25°C
• Refractive Index: 1.51
• PKA: 7.23±0.28(Predicted)
• CAS DataBase Reference: 2-(Dimethylamino)-3',4'-dimethoxyacetophenone(CAS DataBase Reference)
• NIST Chemistry Reference: 2-(Dimethylamino)-3',4'-dimethoxyacetophenone(33061-24-4)
• EPA Substance Registry System: 2-(Dimethylamino)-3',4'-dimethoxyacetophenone(33061-24-4)

Safety Data

• Hazardous Substances Data: 33061-24-4(Hazardous Substances Data)

Usage

White solid

This describes the physical appearance of the compound, indicating that it is a solid with a white color.

Molecular weight

223.27 g/mol This is the mass of one mole of the compound, which is a measure of its size and stability.

Intermediate in the synthesis of pharmaceuticals, organic dyes, and other fine chemicals

This indicates the compound's use in the production of other chemicals, particularly in the pharmaceutical and dye industries.

Photosensitizer

This property means that the compound can generate reactive oxygen species when exposed to light, which is useful in photodynamic therapy for cancer treatment.

Starting material in the production of various other organic compounds

This indicates the compound's versatility and importance in the field of organic synthesis, as it can be used to produce a wide range of other compounds.

InChI:InChI=1/C12H17NO3/c1-13(2)8-10(14)9-5-6-11(15-3)12(7-9)16-4/h5-7H,8H2,1-4H3

Upstream product

• 1835-02-5 2-Bromo-1-(3,4-dimethoxyphenyl)ethanone 
• 124-40-3 dimethyl amine 
• 1131-62-0 1-(3,4-dimethoxyphenyl)ethanone 
• 91-16-7 1,2-dimethoxybenzene 
• 90-05-1 2-methoxy-phenol 

Downstream Products

• 2970-95-8 1-(3, 4-dimethoxyphenyl)-2-dimethylaminoethanol 
• 1616788-82-9 [2-(3, 4-dimethoxyphenyl)-2-phenoxyethyl]dimethylamine 
• 1616788-83-0 [2-(3, 4-dimethoxyphenyl)-2-phenoxyethyl]methylcarbamic acid ethyl ester 
• 23330-76-9 6,7-dimethoxy-4-(4-methoxyphenyl)-2-methyl-1, 2, 3, 4-tetrahydroisoquinoline 
• 1616788-86-3 [2-(3,4-dimethoxyphenyl)-2-phenoxyethyl]methylamine 
• 1616788-87-4 [2-(3,4-dimethoxyphenyl)-2-phenoxyethyl]methylamine 
• 1616781-25-9 4-(6,7-dimethoxy-2-methyl-1, 2, 3, 4-tetrahydroisoquinolin-4-yl)phenol 
• 19751-75-8 (R)-(-)-1-(3,4-dimethoxyphenyl)-2-(dimethylamino)ethanol 
• 150-10-7 1-(3,4-dihydroxy-phenyl)-2-dimethylamino-ethanone 

Relevant articles and documents

New synthesis of (±)-cherylline and mono- and dimethyl ethers

The synthesis of 4-aryl-1,2,3,4-tetrahydroisoquinolines is achieved via the ether rearrangement methodology. Subsequent reactions yielded cherylline and ether derivatives of amaryllidaceac alkaloids. Copyright

Asymmetric synthesis of β-dialkylamino alcohols by transfer hydrogenation of α-dialkylamino ketones

Transfer hydrogenation of representative aryl and heteroaryl dialkylaminomethyl ketones with formic acid-triethylamine, catalyzed by RuCl[(R,R)-TsDPEN](η-p-cymene), produces the corresponding β-dialkylamino alcohols, 97-99% ee, in 50-73% yields. Asymmetric synthesis of (R)-macromerine, 98% ee, the cactus Coryphantha macromeris alkaloid, is also described.