330675-45-1Relevant academic research and scientific papers
An environmentally friendly synthesis of michlers ketone analogues in water
Shirinian, Valerii Z.,Shimkin, Alexey A.,Lonshakov, Dmitry V.,Mailyan, Artur K.,Lvov, Andrey G.,Krayushkin, Michail M.
experimental part, p. 527 - 531 (2012/04/17)
An environmentally friendly method for the synthesis of a series of novel, unsymmetrical Michlers ketone analogues, [4-(dialkylamino)phenyl](aryl) methanones, via nucleophilic aromatic substitution of (fluorophenyl)(aryl) methanones with various amines in water- is described. The reaction products are formed in high yields and additional purification is not required. The aqueous solvent and unreacted amines can be recycled. Georg Thieme Verlag Stuttgart · New York.
