33074-17-8Relevant articles and documents
Solvent-Controlled α-Monobromination, α,α-Dibromination or Imidation of 1,3-Diketones with N-Bromosuccinimide
Zou, Liang-Hua,Li, Yan-Chun,Li, Ping-Gui,Zhou, Jing,Wu, Zhimeng
supporting information, p. 5639 - 5643 (2018/10/05)
In this work, we present a solvent-controlled regioselective method for α-monobromination, dibromination or imidation of 1,3-diketones with N-bromosuccinimide under simple reaction conditions. The employment of solvents plays a key role on the reaction selectivity providing α-monobrominated, dibrominated and imidated products. Visible light irradiation accelerates the dibromination reaction of 1,3-diketones. In particular, one important solvent was found to be highly effective for the imidation of 1,3-diketones under base-free condition.