330796-25-3

Basic information

• Product Name: 1-(2,6-dichloropyridin-4-yl)-3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-ylmethyl]urea
• Synonyms: 1-(2,6-dichloropyridin-4-yl)-3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-ylmethyl]urea
• CAS NO: 330796-25-3
• Molecular Weight: 458.279
• Mol File: 330796-25-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: 1-(2,6-dichloropyridin-4-yl)-3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-ylmethyl]urea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(2,6-dichloropyridin-4-yl)-3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-ylmethyl]urea(330796-25-3)
• EPA Substance Registry System: 1-(2,6-dichloropyridin-4-yl)-3-[3-(4-fluorophenyl)-4-oxo-3,4-dihydroquinazolin-2-ylmethyl]urea(330796-25-3)

Safety Data

• Hazardous Substances Data: 330796-25-3(Hazardous Substances Data)

Upstream product

• 330796-23-1 2-aminomethyl-3-(4-fluoro-phenyl)-3H-quinazolin-4-one 
• 159178-03-7 2,6-dichloro-4-isocyanatopyridine 
• 330796-22-0 [3-(4-fluoro-phenyl)-4-oxo-3,4-dihydro-quinazolin-2-ylmethyl]-carbamic acid benzyl ester 
• 55301-19-4 2-(2-benzyloxycarbonylamino-acetylamino)-benzoic acid 
• 133010-41-0 2-(2-benzyloxycarbonylamino-acetylamino)-benzoic acid methyl ester 
• 134-20-3 2-carbomethoxyaniline 

Relevant articles and documents

Mediators of hedgehog signaling pathways, compositions and uses related thereto

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.

Mediators of hedgehog signaling pathways, compositions and uses related thereto

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growt