330796-33-3

Upstream product

• 5345-47-1 2-aminopyridin-3-carboxylic acid 
• 371-40-4 4-fluoroaniline 
• 330796-32-2 2-ethylpyrido[2,3-d][1,3]oxazin-4-one 

Downstream Products

• 330796-36-6 1-{1-[3(4-fluorophenyl)-4-oxo-3,4-dihydropyrido[2,3-d]pyrimidin-2-yl]ethyl}-1-methyl-3-(3-trifluoromethylphenyl)urea 
• 330796-35-5 3-(4-fluorophenyl)-2-(1-methylaminoethyl)-3H-pyrido[2,3-d]pyrimidin-4-one 
• 330796-34-4 2-(1-bromoethyl)-3-(4-fluorophenyl)-3H-pyrido[2,3-d]pyrimidin-4-one 

Relevant academic research and scientific papers

Mediators of hedgehog signaling pathways, compositions and uses related thereto

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growth state, e.g., to agonize a normal ptc pathway or antagonize hedgehog activity.

Mediators of hedgehog signaling pathways, compositions and uses related thereto

The present invention makes available methods and reagents for inhibiting aberrant growth states resulting from hedgehog gain-of-function by contacting the cell with a hedgehog antagonist, such as a small molecule, in a sufficient amount to aberrant growt