330833-68-6

Upstream product

• 148612-47-9 2-amino-5-methyl-7-phenyl-4,7-dihydro-1,2,4-triazolo[1,5-a]pyrimidine 

Downstream Products

• 1325222-29-4 2-methyl-8-oxo-4-phenyl-1,2,3,4,7,8,9,10-octahydro[1,2,4]triazolo[1,5-a:4,3-a']dipyrimidin-5-ium chloride 
• 1534330-23-8 C₁₅H₁₈ClN₅O 
• 1329168-05-9 2-methyl-8-oxo-4-phenyl-1,2,3,4,9,10-hexahydro-8H-[1,2,4]triazolo[1,5-a:4,3-a']dipyrimidin-5-ium-7-ide 

Relevant academic research and scientific papers

2-Amino-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidines: Synthesis and reactions with electrophilic reagents

The hydrogenation of 2-amino-5-R-7-R′-4,7-dihydro-1,2,4-triazolo[1,5- a]pyrimidines with NaBH4 led to the formation of 2-amino-5-R-7- R′-4,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a]pyrimidines. Acylation, sulfonylation, and alkylation of these compounds depending on conditions and the reagent character occur at the amino group, atoms N3 or N 4. The treatment with alkali of 2-amino-3-benzyl-5-R-7-R′-4,5, 6,7-tetrahydro-1,2,4-triazolo-[1,5-a]pyrimidinium bromide resulted in 2-amino-3-benzyl-5-R-7-R′-3,5,6,7-tetrahydro-1,2,4-triazolo[1,5-a] -pyrimidine, similar reaction of 2-acetamido-3-benzyl-5-R-7-R′-4,5,6,7- tetrahydro-1,2,4-triazolo[1,5-a]-pyrimidinium bromide gave a mesoionic product of a hydrogen elimination from the amide nitrogen atom.