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8-phenyl-5-(propan-2-yl)[1,3]dioxolo[4,5-g]quinazolin-6(5H)-one is a complex organic compound characterized by a quinazolinone core, which is a fused ring system consisting of a quinazoline and a dioxolane. The quinazoline ring is a tricyclic structure with one benzene ring and two nitrogen atoms, while the dioxolane ring is a five-membered ring containing two oxygen atoms. In this specific compound, the 8-position of the quinazoline is substituted with a phenyl group, and the 5-position is substituted with a propan-2-yl group. The compound is a 5H-one, indicating that it has a hydrogen atom at the 5-position of the quinazoline ring, which can participate in hydrogen bonding or other interactions. 8-phenyl-5-(propan-2-yl)[1,3]dioxolo[4,5-g]quinazolin-6(5H)-one is likely to be of interest in medicinal chemistry due to its potential biological activities, as quinazolinone derivatives are known to have a range of pharmacological properties.

33095-89-5

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33095-89-5 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 33095-89-5 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,3,0,9 and 5 respectively; the second part has 2 digits, 8 and 9 respectively.
Calculate Digit Verification of CAS Registry Number 33095-89:
(7*3)+(6*3)+(5*0)+(4*9)+(3*5)+(2*8)+(1*9)=115
115 % 10 = 5
So 33095-89-5 is a valid CAS Registry Number.

33095-89-5SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 8-phenyl-5-propan-2-yl-[1,3]dioxolo[4,5-g]quinazolin-6-one

1.2 Other means of identification

Product number -
Other names 5-Isopropyl-8-phenyl-1,3-dioxolo(4,5-g)quinazolin-6(5H)-one

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:33095-89-5 SDS

33095-89-5Relevant academic research and scientific papers

Substituted quinazolines and analogs and use thereof

-

, (2008/06/13)

The invention relates to novel quinazolines and heterocycles which are antagonists or positive modulators of AMPA receptors, and the use thereof for treating, preventing or ameliorating neuronal loss associated with stroke, global and focal ischemia, CNS trauma, hypoglycemia and surgery, as well as treating or ameliorating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, Parkinson's disease and Down's syndrome, treating, preventing or ameliorating the adverse consequences of the overstimulation of the excitatory amino acids, treating, preventing or ameliorating anxiety, psychosis, convulsions, chronic pain, glaucoma, retinitis, urinary incontinence, muscular spasm and inducing anesthesia, as well as for treating or ameliorating the adverse consequences of excitatory amino acid deficiency such as schizophrenia, myoclonus. Alzheimer's disease and malnutrition and neural maldevelopment, and as cognition and learning enhancers.

Analgesic and myotonolytic preparations

-

, (2008/06/13)

Compositions having enhanced analgesic and myotonolytic activity comprising as active agents (a) an analeptically active quinazolinone and (b) a centrally acting myotonolytic.

Antiinflammatory Properties of 8-Aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones

Houlihan, William J.,Cooke, George,Bochoven, Richard Van,Perrine, John,Takesue, Edward I.,Jukniewicz, E.

, p. 1110 - 1113 (2007/10/02)

A series of 8-aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones was prepared and evaluated for antiinflammatory activity.The 8-phenyl-, 8-(3-fluorophenyl)-, and 8-(4-fluorophenyl)-2H-1,3-dioxoloquinazolin-6(5H)-ones and the 8-phenyl-2H-1,3-dioxoloquinazolin-6(5H)-thione were found to exhibit activity in the range of indomethacin and proquazone.

Preparation of quinazolin-2(1H)-ones

-

, (2008/06/13)

The invention provides a process for the production of 4-phenyl-2(1H)-quinazolinones by cyclising a corresponding 2-aminobenzophenone with urea or an alkylcarbamate in the presence of an aromatic acid. The products are known anti-inflammatory agents.

2-Amino-4,5-methylenedioxyphenyl nitriles

-

, (2008/06/13)

2-Amino-4,5-methylenedioxyphenyl nitriles are useful as intermediates for 2-amino-4,5-methylenedioxybenzophenonimines when reacted with a phenyl lithium or phenyl magnesium halide.

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