33095-94-2

Basic information

• Product Name: 1-(1,3-benzodioxol-5-yl)-1-isopropylurea
• Synonyms: 1-(1,3-benzodioxol-5-yl)-1-isopropylurea;1-(1,3-benzodioxol-5-yl)-1-propan-2-ylurea
• CAS NO: 33095-94-2
• Molecular Formula: C₁₁H₁₄N₂O₃
• Molecular Weight: 222.24046
• EINECS: 251-378-0
• Mol File: 33095-94-2.mol
• Article Data: 3

Chemical Properties

• Boiling Point: 375.5°C at 760 mmHg
• Flash Point: 180.9°C
• Appearance: /
• Density: 1.286g/cm³
• Vapor Pressure: 7.75E-06mmHg at 25°C
• Refractive Index: 1.605
• CAS DataBase Reference: 1-(1,3-benzodioxol-5-yl)-1-isopropylurea(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(1,3-benzodioxol-5-yl)-1-isopropylurea(33095-94-2)
• EPA Substance Registry System: 1-(1,3-benzodioxol-5-yl)-1-isopropylurea(33095-94-2)

Safety Data

• Hazardous Substances Data: 33095-94-2(Hazardous Substances Data)

Usage

General Description

1-(1,3-benzodioxol-5-yl)-1-isopropylurea, also known as 5-Allyl-1,3-benzodioxole-5-carboxamide, is a chemical compound with the molecular formula C11H13N3O3. It is a urea derivative and is classified as a drug and pesticide intermediate. 1-(1,3-benzodioxol-5-yl)-1-isopropylurea is believed to have potential as a central nervous system stimulant and has been researched for its potential use in the treatment of various neurological and psychiatric disorders. 1-(1,3-benzodioxol-5-yl)-1-isopropylurea is also used in the synthesis of various pharmaceuticals and agrochemicals due to its diverse chemical properties. However, further research and testing are needed to fully understand its potential applications and effects.

InChI:InChI=1/C11H14N2O3/c1-7(2)13(11(12)14)8-3-4-9-10(5-8)16-6-15-9/h3-5,7H,6H2,1-2H3,(H2,12,14)

Upstream product

• 14268-66-7 benzo[1,3]dioxolo-5-ylamine 
• 917-61-3 sodium isocyanate 
• 10368-14-6 N-isopropyl-3,4-(methylenedioxy)aniline 

Downstream Products

• 85575-64-0 3-(5-Isopropyl-6-oxo-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]quinazolin-8-yl)-benzoic acid 
• 33095-80-6 1-isopropyl-4-(p-fluorophenyl)-6,7-methylenedioxy-3,4-dihydro-2(1H)-quinazolinone 
• 82448-21-3 4-(5-Isopropyl-6-oxo-5,6,7,8-tetrahydro-[1,3]dioxolo[4,5-g]quinazolin-8-yl)-benzoic acid 
• 33095-84-0 1-isopropyl-4-(o-methylphenyl)-6,7-methylenedioxy-3,4-dihydro-2(1H)-quinazolinone 
• 33095-77-1 1-isopropyl-4-(m-methoxyphenyl)-6,7-methylenedioxy-3,4-dihydro-2(1H)-quinazolinone 
• 33095-81-7 1-isopropyl-4-(3,4-dichlorophenyl)-6,7-methylenedioxy-3,4-dihydro-2(1H)-quinazolinone 
• 33095-90-8 1-isopropyl-4-(m-fluorophenyl)-6,7-methylenedioxy-3,4-dihydro-2(1H)-quinazolinone 
• 33140-91-9 1-isopropyl-4-(m-nitrophenyl)-6,7-methylenedioxy-2(1H)-quinazolinone 
• 33095-72-6 1-Isopropyl-4-(o-nitro-phenyl)-6,7-methylendioxy-2(1H)chinazolinon 
• 41953-54-2 1-isopropyl-4-(3,4-dichlorophenyl)-6,7-methylenedioxy-2(1H)-quinazolinone 
• 33100-28-6 1-isopropyl-4-(m-methoxyphenyl)-6,7-methylenedioxy-2(1H)-quinazolinone 
• 33095-70-4 1-isopropyl-6,7-methylenedioxy-4-(m-fluorophenyl)-quinazolin-2(1H)-one 
• 33140-92-0 1-isopropyl-4-(o-methylphenyl)-6,7-methylenedioxy-2(1H)-quinazolinone 
• 33140-90-8 1-isopropyl-4-(p-methylphenyl)-6,7-methylenedioxy-2(1H)-quinazolinone 

Relevant articles and documents

Substituted quinazolines and analogs and use thereof

The invention relates to novel quinazolines and heterocycles which are antagonists or positive modulators of AMPA receptors, and the use thereof for treating, preventing or ameliorating neuronal loss associated with stroke, global and focal ischemia, CNS trauma, hypoglycemia and surgery, as well as treating or ameliorating neurodegenerative diseases including Alzheimer's disease, amyotrophic lateral sclerosis, Huntington's disease, Parkinson's disease and Down's syndrome, treating, preventing or ameliorating the adverse consequences of the overstimulation of the excitatory amino acids, treating, preventing or ameliorating anxiety, psychosis, convulsions, chronic pain, glaucoma, retinitis, urinary incontinence, muscular spasm and inducing anesthesia, as well as for treating or ameliorating the adverse consequences of excitatory amino acid deficiency such as schizophrenia, myoclonus. Alzheimer's disease and malnutrition and neural maldevelopment, and as cognition and learning enhancers.

Antiinflammatory Properties of 8-Aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones

A series of 8-aryl-5-isopropyl-2H-1,3-dioxoloquinazolin-6(5H)-ones and -thiones was prepared and evaluated for antiinflammatory activity.The 8-phenyl-, 8-(3-fluorophenyl)-, and 8-(4-fluorophenyl)-2H-1,3-dioxoloquinazolin-6(5H)-ones and the 8-phenyl-2H-1,3-dioxoloquinazolin-6(5H)-thione were found to exhibit activity in the range of indomethacin and proquazone.