330985-33-6

Upstream product

• 188660-16-4 (S)-N-Carbobenzoxy-3-hydroxy-1,2,3,4-tetrahydropyridine 
• 108-24-7 acetic anhydride 

Downstream Products

• 403499-10-5 2-tert-butoxycarbonylmethyl-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidine-1-carboxylic acid tert-butyl ester 
• 403499-08-1 [1-benzyl-5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-2-yl]-acetic acid tert-butyl ester 
• 403499-09-2 [5-(tert-butyl-diphenyl-silanyloxymethyl)-pyrrolidin-2-yl]-acetic acid tert-butyl ester 
• 403499-05-8 ((2R,5S)-1-Benzyl-5-methanesulfonyloxy-piperidin-2-yl)-acetic acid tert-butyl ester 
• 403499-06-9 ((2R,5R)-5-Acetoxymethyl-1-benzyl-pyrrolidin-2-yl)-acetic acid tert-butyl ester 
• 403499-03-6 ((2R,5S)-5-Acetoxy-1-benzyl-piperidin-2-yl)-acetic acid tert-butyl ester 
• 403499-04-7 ((2R,5S)-1-Benzyl-5-hydroxy-piperidin-2-yl)-acetic acid tert-butyl ester 
• 403499-07-0 ((2R,5R)-1-Benzyl-5-hydroxymethyl-pyrrolidin-2-yl)-acetic acid tert-butyl ester 
• 179915-15-2 trans-5-Acetoxy-2-allyl-1-carbobenzoxypiperidine 

Relevant academic research and scientific papers

Diastereoselective synthesis of 3,5-trans-(+)-(3R,5R)-3-carbomethoxycarbapenam from 3-hydroxypyridine: Questioning the stereochemical assignment of the natural product

An enantio- and diastereoselective synthesis of the methyl ester of 3,5-trans-(3R,5R)-carbapenam-3-carboxylic acid from 3-hydroxypyridine via (2R,5S)-trans-5-acetoxy-2-allylpiperidine has been achieved by employing the piperidine-pyrrolidine ring-contract