33105-81-6

Basic information

• Product Name: DL-tert-Leucine
• Synonyms: TERT-BUTYLGLYCINE;Valine, 3-methyl-;DL-Tle-OH;tert-DL-LEUCINE extrapure;tert-leucine;(±)-2-Amino-3,3-dimethylbutyric acid, DL-α-tert-Butylglycine;DL-tert-Butylglycine,99%;DL-tert-ButylglycineDL-tert-Leucine
• CAS NO: 33105-81-6
• Molecular Formula: C₆H₁₃NO₂
• Molecular Weight: 131.17
• EINECS: 1308068-626-2
• Product Categories: Leucine [Leu, L];Unusual Amino Acids;Peptide
• Mol File: 33105-81-6.mol
• Article Data: 2

Chemical Properties

• Melting Point: >300 °C(lit.)
• Boiling Point: 242.49°C (rough estimate)
• Flash Point: 85.5 °C
• Appearance: /Solid
• Density: 1.0975 (rough estimate)
• Refractive Index: 1.4240 (estimate)
• Storage Temp.: Store at RT.
• Solubility: H2O: 0.1 g/mL, clear, colorless
• PKA: 2.39±0.12(Predicted)
• Water Solubility: soluble
• BRN: 1721823
• CAS DataBase Reference: DL-tert-Leucine(CAS DataBase Reference)
• NIST Chemistry Reference: DL-tert-Leucine(33105-81-6)
• EPA Substance Registry System: DL-tert-Leucine(33105-81-6)

Safety Data

• Safety Statements: 22-24/25
• WGK Germany: 3
• Hazardous Substances Data: 33105-81-6(Hazardous Substances Data)

Usage

Chemical Properties

white powder

InChI:InChI=1/C6H13NO2/c1-6(2,3)4(7)5(8)9/h4H,7H2,1-3H3,(H,8,9)/p-1

Upstream product

• 26782-71-8 D-tert-leucine 

Downstream Products

• 3850-31-5 methyl tert-leucinate 
• 3981-38-2 4-tert-butyl-oxazolidine-2,5-dione 
• 68222-59-3 2(S)-{(benzyloxycarbonyl)amino}-3,3-dimethylbutanoic acid 
• 22146-58-3 (+/-)-2-acetylamino-3,3-dimethylbutyric acid 
• 72756-21-9 2-(benzoylamino)-3,3-dimethylbutanoic acid 
• 69557-36-4 3,3-dimethyl-2-(toluene-4-sulfonylamino)-butyric acid 
• 69610-03-3 Ethyl tert-leucinate 
• 69557-34-2 ethyl (S)-2-amino-3,3-dimethylbutanoate 
• 253178-21-1 ethyl (R)-2-amino-3,3-dimethylbutanoate 
• 92752-26-6 2-{[(Diphenylphosphanyl)-methyl]-amino}-3,3-dimethyl-butyric acid 
• 71953-55-4 2-phenyl-4-tert-butyloxazolin-5(4H)-one 
• 20859-02-3 L-tert-Leucine 
• 92571-59-0 D-2-formylamino-3,3-dimethyl-butyric acid 
• 1218229-61-8 C₁₃H₁₇ClN₂O₃ 

Relevant articles and documents

PROCESS FOR THE PREPARATION OF ENANTIOMERICALLY PURE tert-LEUCINE

Enantiomerically pure L-tert-leucine and D-tert-leucine were prepared from (DL)-tert-leucine by diastereomeric salt formation using dibenzoyl-d-tartaric acid as the resolving agent.