33108-93-9Relevant academic research and scientific papers
A carbonyl wo containing heptafluoro isopropyl ether compound, preparation method and application thereof
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Paragraph 0099; 0100; 0101; 0107; 0108; 0109, (2017/08/02)
The present invention discloses a heptafluoroisopropyl-containing carbonyl oxime ether compound, which has the following structural general formula (I), wherein each substituent is defined in the instruction. The present invention further provides a preparation method and applications of the compound. The compound of the present invention is particularly suitable for prevention and control of Mythimna separate, AphiscraccivoraKoch, Tetranychus cinnabarinus, cucumber downy mildew bacteria and rice sheath blight disease bacteria.
PESTICIDALLY ACTIVE KETONE AND OXIME DERIVATIVES
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Page 40, (2008/06/13)
Compounds of formula (I), wherein A0, A1, and A2 are each independently of the others a bond or a Cl-C6alkylene bridge; A3 is a Cl-C6alkylene bridge which is unsubstituted or substituted by from one to six identical or different substituents selected from halogen and C3-C8cycloalkyl; Y is, for example, 0, S, SO or S02; M is 0 or NOR6, X1, and X2 are each independently of the other fluorine, chlorine or bromine; R1, R2and R3 are, for example, H, halogen, OH, SH, CN, nitro, C1-C6alkyl, Cl-C6haloalkyl, Cl-C6alkylcarbonyl, C2-C6alkenyl, C2-C6haloalkenyl or C2-C6alkynyl; Q is, for example, O, S, SO or SO2; W is, for example, 0, S, SO, SO2, -C(=O)-O- or -0-C(=O)-; T is, for example, a bond, 0, S, SO, S02, -C(=O)-O-or -0-C(=O)-; D is CH or N; R4 is, for example, H, halogen, OH, SH, CN, nitro, Cl-C6alkyl or C1-C6haloalkyl; R5is, for example, Cl-Cl2alkyl, C3-C8cycloalkyl or -N(R7)2; R7 is H, C1-C6alkyl, Cl-C3haloalkyl, Cl-C6alkylcarbonyl, Cl-C3haloalkylcarbonyl, Cl-C6alkoxycarbonyl, C3-C8Cycloalkyl, C3-C8 cycloalkylcarbonyl or formyl; k is 0, 1, 2, 3 or 4; m is 1 or 2; and q is 0, 1 or 2; and, where applicable, their possible E/Z isomers, E/Z isomeric mixtures and/or tautomers, in each case in free form or in salt form, a process for the preparation of those compounds and their use, pesticidal compositions in which the active ingredient has been selected from those compounds and agrochemically acceptable salts thereof, and a process for the preparation of those compositions and their use, to plant propagation material treated with those compositions, and a method of controlling pests.
Nonquaternary cholinesterase reactivators. 4. Dialkylaminoalkyl thioesters of α-keto thiohydroximic acids as reactivators of ethyl methylphosphonyl- and 1,2,2-trimethylpropyl methylphosphonyl-acetylcholinesterase in vitro
Bedford,Miura,Bottaro,Howd,Nolen III
, p. 1689 - 1696 (2007/10/02)
In the search for improved lipophilic centrally active acetylcholinesterase (AChE) antidotes, a series of α-keto thiohydroximates were prepared and evaluated for their ability to reactivate AChEs inhibited by ethyl p-nitrophenyl methylphosphonate (EPMP) and soman (GD). The compounds conformed to the general structure 4-RC6H5C-(O)C(NOH)S(CH2)(n)N+R'R''·X- where R = H, CH3, F, Br, Cl, OCH3, CN; R' = CH3, C2H5, i-C3H7; R'' = H, CH3; X = Cl, I; and n = 2, 3. In this series, varying R substituents on the aryl ring produced compounds with oxime pK(a) values from 6.8 to 8.0, optimum for an AChE reactivator. Increasing lipophilicity of the amine segment correlated with reactivator potency, as did electron-withdrawing groups on the aryl moiety, presumably due to increased binding to hydrophobic sites surrounding the AChE active site. The in vitro reactivation potency of the α-keto thiohydroximates approaches and even surpasses that of 2-PAM and toxogonin for GD-inhibited AChE. These initial findings point to additional structure-activity relationships to assist in the design of improved antidotal compounds.
1-Chloro-1-p-methoxybenzoylformaldoxime-N-methylcarbamate
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, (2008/06/13)
The compound 1-chloro-1-p-methoxybenzoylformaldoxime-N-methylcarbamate is useful as an antifungal agent.
