33123-68-1

Usage

Uses

Used in Pharmaceutical Industry:
Oxazole-2-carboxylic acid is utilized as a crucial building block for the synthesis of various drug molecules, contributing to the development of new pharmaceuticals with potential therapeutic applications.
Used in Drug Discovery and Development:
It serves as a valuable component in the discovery and development of new drugs, owing to its unique structure and reactivity, which can be leveraged to create molecules with specific biological activities.
Used in Research and Chemical Synthesis:
Oxazole-2-carboxylic acid is employed in research settings and chemical synthesis processes, where its properties can be explored and harnessed to create new compounds with potential applications in various fields.
Used in Organic Chemistry for the Creation of New Compounds:
It has potential applications in the field of organic chemistry, where it can be used to synthesize new compounds with biological activities, expanding the scope of chemical and pharmaceutical research.

Upstream product

• 33115-97-8 ethyl 2-oxo-2-((2-oxopropyl)amino)acetate 
• 754202-89-6 ethyl 2-((2-hydroxypropyl)amino)-2-oxoacetate 

Downstream Products

• 888022-42-2 (5-methyloxazol-2-yl)methanol 

Relevant academic research and scientific papers

FUNCTIONALIZED AMINOTRIAZINES

The present invention relates to novel antagonists of the A2B adenosine receptor and pharmaceutical compositions comprising said antagonists as well as their uses for the treatment and prevention of disorders known to be susceptible to improvement by anta

SUBSTITUTED XANTHINES AND METHODS OF USE THEREOF

Compounds, compositions and methods are described for inhibiting the TRPC5 ion channel and disorders related to TRPC5.

SPIROHYDANTOIN COMPOUNDS AND THEIR USE AS SELECTIVE ANDROGEN RECEPTOR MODULATORS

The present invention relates to a compound of formula (1-1 ) in free form or in pharmaceutically acceptable salt form in which the substituents are as defined in the specification; to its preparation, to its use as a medicament and to medicaments comprising it. The present invention further provides a combination of pharmacologically active agents and a pharmaceutical composition.

NOVEL SPIROPIPERIDINE COMPOUNDS

A compound of the formula: or a pharmaceutically acceptable salt thereof as well as a pharmaceutical composition, and a method for treating diabetes.

Cyclization of propargylic amides: Mild access to oxazole derivatives

The substrate scope, the mechanistic aspects of the gold-catalyzed oxazole synthesis, and substrates with different aliphatic, aromatic, and functional groups in the side chain were investigated. Even molecules with several propargyl amide groups could easily be converted, delivering di- and trioxazoles with interesting optical properties. Furthermore, the scope of the gold(I)-catalyzed alkylidene synthesis was investigated. Further functionalizations of these isolable intermediates of the oxazole synthesis were developed and chelate ligands can be obtained. The use of Barluenga's reagent offers a new and mild access to the synthetically valuable iodoalkylideneoxazoles from propargylic amides, this reagent being superior to other sources of halogens.