331258-42-5

Basic information

• Product Name: methyl N-benzoyl-7-azabicyclo[2.2.1]heptane-1-carboxylate
• Synonyms: methyl N-benzoyl-7-azabicyclo[2.2.1]heptane-1-carboxylate
• CAS NO: 331258-42-5
• Molecular Weight: 259.305
• Mol File: 331258-42-5.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: methyl N-benzoyl-7-azabicyclo[2.2.1]heptane-1-carboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: methyl N-benzoyl-7-azabicyclo[2.2.1]heptane-1-carboxylate(331258-42-5)
• EPA Substance Registry System: methyl N-benzoyl-7-azabicyclo[2.2.1]heptane-1-carboxylate(331258-42-5)

Safety Data

• Hazardous Substances Data: 331258-42-5(Hazardous Substances Data)

Upstream product

• 20989-42-8 N-benzoylserine methyl ester 
• 1330783-88-4 N-(3-oxo-2-oxabicyclo[2.2.2]oct-4-yl)benzamide 
• 98-88-4 benzoyl chloride 
• 331258-40-3 methyl 1-benzimido-4-oxocyclohexane-1-carboxylate 
• 1239450-42-0 2-benzoylamino-3-methoxy-3-oxo-propanol benzoate 
• 331258-41-4 methyl 1-benzimido-c-4-methanesulfonyloxycyclohexane-r-1-carboxylate 
• 24153-31-9 2-benzoylaminoacrylic acid methyl ester 

Downstream Products

• 182137-60-6 7-[(benzyloxy)carbonyl]-7-azabicyclo[2.2.1]heptane-1-carboxylic acid 
• 182137-63-9 benzyl 1-(chlorocarbonyl)-7-azabicyclo[2.2.1]heptane-7-carboxylate 
• 1330783-90-8 benzyl 1-(6-bromo-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl)-7-azabicyclo[2.2.1]heptane-7-carboxylate 
• 1330783-91-9 benzyl 1-{6-[1-(tert-butoxycarbonyl)-3-methyl-1H-pyrazol-4-yl]-4-oxo-3,4-dihydrothieno[3,2-d]pyrimidin-2-yl}-7-azabicyclo[2.2.1]heptane-7-carboxylate 
• 331258-38-9 7-azabicyclo[2.2.1]heptane-1-carboxylic acid 
• 431947-10-3 N-benzoyl-7-azabicyclo[2.2.1]heptane-1-carboxylic acid 2-thioxo-2H-pyridin-1-yl ester 
• 188624-96-6 N-benzoyl-7-azabicyclo[2.2.1]heptane 
• 431947-09-0 N-benzoyl-7-azabicyclo[2.2.1]heptane-1-carboxylic acid 
• 441353-52-2 Boc-Ach-OH 

Relevant articles and documents

Bruton's tyrosine kinase inhibitor

The invention relates to a compound with a formula I and a pharmaceutically acceptable salt, a solvent compound, an active metabolite, a polycrystalline compound, an ester, an isomer or a prodrug thereof, a pharmaceutical composition containing the compound in the formula I, and application using the same as a selective Bruton's tyrosine kinase inhibitor to prepare a medicine for preventing or treating heterologous immunity diseases and self immunity diseases or cancers. The formula is shown in the specification.

New synthesis of 7-azabicyclo[2.2.1]heptane-1-carboxylic acid

This report describes a new synthetic route to 7-azabicyclo[2.2.1]heptane-1-carboxylic acid (Ahc), a constrained proline analogue, in which the key step is the Diels-Alder reaction using methyl 2-benzamidoacrylate as dienophile.