331268-68-9Relevant articles and documents
Synthesis of Novel Nucleoside Analogues Built on a Bicyclo[4.1.0]heptane Scaffold
Dom?nguez-Pérez, Beatriz,Ferrer, éric,Figueredo, Marta,Maréchal, Jean-Didier,Balzarini, Jan,Alibés, Ramon,Busqué, Félix
, p. 9495 - 9505 (2015/10/12)
A new class of carbocyclic nucleoside analogues built on a bicyclo[4.1.0]heptane scaffold, a perspective novel pseudosugar pattern, have been conceived as anti-HSV agents on the basis of initial protein-ligand docking studies. The asymmetric synthesis of a series of these compounds incorporating different nucleobases has been efficiently completed starting from 1,4-cyclohexanedione.
New, highly efficient syntheses of rac-, (R)- and (S)-4-hydroxy-2-cyclohexenone
De March, Pedro,Escoda, Maria,Figueredo, Marta,Font, Josep,Garcia-Garcia, Elena,Rodriguez, Sonia
, p. 4473 - 4483 (2007/10/03)
Both enantiomers of 4-hydroxy-2-cyclohexenone have been synthesised from chiral p-benzoquinone equivalents through very short and simple sequences in good overall yields.