331268-68-9

Upstream product

• 169267-16-7 4,4-<(1R,2R)-1,2-(diphenyl)ethylenedioxi>-2,5-cyclohexadienone 
• 331268-67-8 4,4-[(1R,2R)-(1,2-diphenylethylene)dioxy]-2-cyclohexenone 
• 214892-30-5 (2R,3R)-(+)-2,3-diphenyl-1,4-dioxaspiro[4.5]decan-8-one 
• 637-88-7 1,4-Cyclohexanedione 

Downstream Products

• 132746-89-5 (+)-(R)-4-hydroxycyclohex-2-enone 
• 1130727-82-0 N₃-benzoyl-1-[(2'R,3'R,8'S)-2',3'-diphenyl-1',4'-dioxaspiro[4.5]dec-6'-en-8'-yl]uracil 
• 1130727-74-0 C₂₅H₂₁ClN₄O₂ 
• 1130727-75-1 6-chloro-9-[(2'R,3'R,8'S)-2',3'-diphenyl-1',4'-dioxaspiro[4.5]dec-6'-en-8'-yl]purine 
• 1130727-77-3 (2R,3R,8R)-2,3-diphenyl-8-ethoxycarbonate-1,4-dioxaspiro[4.5]dec-6-ene 

Relevant academic research and scientific papers

Synthesis of Novel Nucleoside Analogues Built on a Bicyclo[4.1.0]heptane Scaffold

A new class of carbocyclic nucleoside analogues built on a bicyclo[4.1.0]heptane scaffold, a perspective novel pseudosugar pattern, have been conceived as anti-HSV agents on the basis of initial protein-ligand docking studies. The asymmetric synthesis of a series of these compounds incorporating different nucleobases has been efficiently completed starting from 1,4-cyclohexanedione.

Enantiodivergent synthesis of cyclohexenyl nucleosides

An enantiodivergent synthesis of several cyclohexenyl nucleosides has been efficiently completed starting from the enantiopure hydrobenzoin-derived monoketal of cyclohex-2-en-1,4-dione, (+)-5. Stereodiversity was accomplished on the base coupling step. Th

New, highly efficient syntheses of rac-, (R)- and (S)-4-hydroxy-2-cyclohexenone

Both enantiomers of 4-hydroxy-2-cyclohexenone have been synthesised from chiral p-benzoquinone equivalents through very short and simple sequences in good overall yields.