331283-95-5

Basic information

• Product Name: H-Dmt-NH₂
• CAS NO: 331283-95-5
• Molecular Weight: 208.26
• Mol File: 331283-95-5.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: H-Dmt-NH₂(CAS DataBase Reference)
• NIST Chemistry Reference: H-Dmt-NH₂(331283-95-5)
• EPA Substance Registry System: H-Dmt-NH₂(331283-95-5)

Safety Data

• Hazardous Substances Data: 331283-95-5(Hazardous Substances Data)

Upstream product

• 928195-92-0 (S)-2-Amino-3-(4-hydroxy-2,6-dimethyl-phenyl)-propionic acid methyl ester 
• 123715-02-6 H-Dmt 
• 848086-27-1 [1-carbamoyl-2-(4-hydroxy-2,6-dimethyl-phenyl)-ethyl]-carbamic acid tert-butyl ester 

Downstream Products

• 1311406-43-5 H-Dmt-Pro-Phe-Dmt-NH₂ 

Relevant articles and documents

Studies on the structure-activity relationship of 2′,6′- dimethyl-l-tyrosine (Dmt) derivatives: Bioactivity profile of H-Dmt-NH-CH 3

The 2′,6′-dimethyl-l-tyrosine (Dmt) enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides. To further investigate its direct influence on these opioid parameters, we developed a series of compounds (H-Dmt-NH-X). Among them, H-Dmt-NH-CH3 showed the highest affinity (Kiμ = 7.45 nM) equal to that of morphine, partial μ-opioid agonism (Emax = 66.6%) in vitro and a moderate antinociception in mice.