928195-92-0

Basic information

• Product Name: L-Tyrosine, 2,6-dimethyl-, methyl ester
• Synonyms: L-Tyrosine, 2,6-dimethyl-, methyl ester;methyl (S)-2-amino-3-(4-hydroxy-2,6-dimethylphenyl)propanoate
• CAS NO: 928195-92-0
• Molecular Formula: C₁₂H₁₇NO₃
• Molecular Weight: 223.26828
• Mol File: 928195-92-0.mol
• Article Data: 1

Chemical Properties

• Appearance: /
• CAS DataBase Reference: L-Tyrosine, 2,6-dimethyl-, methyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: L-Tyrosine, 2,6-dimethyl-, methyl ester(928195-92-0)
• EPA Substance Registry System: L-Tyrosine, 2,6-dimethyl-, methyl ester(928195-92-0)

Safety Data

• Hazardous Substances Data: 928195-92-0(Hazardous Substances Data)

Upstream product

• 67-56-1 methanol 
• 123715-02-6 H-Dmt 

Downstream Products

• 848086-27-1 [1-carbamoyl-2-(4-hydroxy-2,6-dimethyl-phenyl)-ethyl]-carbamic acid tert-butyl ester 
• 331283-95-5 H-Dmt-NH₂ 

Relevant articles and documents

Studies on the structure-activity relationship of 2′,6′- dimethyl-l-tyrosine (Dmt) derivatives: Bioactivity profile of H-Dmt-NH-CH 3

The 2′,6′-dimethyl-l-tyrosine (Dmt) enhances receptor affinity, functional bioactivity and in vivo analgesia of opioid peptides. To further investigate its direct influence on these opioid parameters, we developed a series of compounds (H-Dmt-NH-X). Among them, H-Dmt-NH-CH3 showed the highest affinity (Kiμ = 7.45 nM) equal to that of morphine, partial μ-opioid agonism (Emax = 66.6%) in vitro and a moderate antinociception in mice.